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伴有乳头溢液的乳腺叶状肿瘤:一例报告

Phyllodes tumor of the breast with nipple discharge: A case report.

作者信息

Jing Pengfei, Wei Bing, Yang Xiaoqin

机构信息

Department of General Surgery.

Department of Pathology.

出版信息

Medicine (Baltimore). 2018 Dec;97(52):e13767. doi: 10.1097/MD.0000000000013767.

DOI:10.1097/MD.0000000000013767
PMID:30593154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6314703/
Abstract

RATIONALE

Phyllodes tumors (PTs) of the breast are rare biphasic fibroepithelial neoplasms which usually present with unilateral palpable breast lumps. Here we reported a case of borderline PTs with multifocal intraductal lesions whose primary clinical manifestation was nipple discharge.

PATIENT CONCERNS

A rare case of PT with nipple discharge in a 26-year-old young lady accepted a wide local excision on her left breast, and the pathological examination turned out to be a malignant phyllodes tumor. After a 12-month follow-up, no local or distant recurrence was observed.

DIAGNOSIS

Borderline PTs with multifocal intraductal lesions INTERVENTIONS:: The patient received wide local excision with clear margin. After the operation, the patient is undergoing surveillance through ultrasonography and physical examination every 3 months.

OUTCOMES

After a follow-up of 12 months, no local or distant recurrence was observed.

LESSONS

The lesions of the PTs are often manifested with unilateral, palpable masses in the breast. There are very few case reports of PTs manifested with nipple discharge in the literature. We should improve the understanding of the multiple clinical manifestations of PTs.

摘要

理论依据

乳腺叶状肿瘤(PTs)是罕见的双相性纤维上皮性肿瘤,通常表现为单侧可触及的乳腺肿块。在此,我们报告一例具有多灶性导管内病变的交界性PTs病例,其主要临床表现为乳头溢液。

患者情况

一名26岁年轻女性,因罕见的伴有乳头溢液的PTs接受了左乳广泛局部切除,病理检查结果为恶性叶状肿瘤。经过12个月的随访,未观察到局部或远处复发。

诊断

具有多灶性导管内病变的交界性PTs

干预措施

患者接受了切缘清晰的广泛局部切除。术后,患者每3个月通过超声检查和体格检查进行监测。

结果

经过12个月的随访,未观察到局部或远处复发。

经验教训

PTs的病变通常表现为乳腺单侧可触及的肿块。文献中很少有PTs表现为乳头溢液的病例报告。我们应提高对PTs多种临床表现的认识。

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Histopathology. 2016 Jan;68(1):5-21. doi: 10.1111/his.12876.
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Genomic landscapes of breast fibroepithelial tumors.乳腺纤维上皮肿瘤的基因组图谱。
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Phyllodes tumor of the breast.乳腺叶状肿瘤
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