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以植物来源的常规脂肪水平的饮食可能逆转冠状动脉疾病。

Diets with customary levels of fat from plant origin may reverse coronary artery disease.

机构信息

NEWSTART Lifestyle Center, Weimar Institute, Weimar, CA, United States; Department of Public Health, Nutrition and Wellness, Andrews University, Berrien Springs, MI, United States.

Department of Public Health, Nutrition and Wellness, Andrews University, Berrien Springs, MI, United States.

出版信息

Med Hypotheses. 2019 Jan;122:103-105. doi: 10.1016/j.mehy.2018.10.027. Epub 2018 Oct 30.

DOI:10.1016/j.mehy.2018.10.027
PMID:30593389
Abstract

The primary cause of death worldwide is heart disease and the most common type of heart disease is coronary artery disease. While coronary artery disease is treated with medications, it responds to lifestyle interventions. A low-fat plant-based diet was designed for reversing coronary artery disease and it is effective in reversing the disease. It has not been tested, however, as far as we know, whether diets with customary levels of fat can also reverse coronary artery disease. Nevertheless, evidence is accumulating to show that atherosclerosis and coronary artery disease are reversed with diets containing customary levels of fat. It has been known that fats of plant origin decrease the risk factors of cardiovascular disease. It is also known that vegans who consume diets with customary levels of fat have the lowest risk of cardiovascular disease. But recent and more specific data show that atherosclerosis was decreased when nuts that are rich in fat were added to a Mediterranean diet while atherosclerosis was increased in the controls. Also, two clinical cases show that coronary artery disease was reversed by low-fat plant-based diets that were supplemented with fat-rich foods of plant origin. These data, then, provide evidence that coronary artery disease may be reversed with a diet containing customary levels of fat from plant sources. We hypothesize that coronary artery disease may be reversed by diets with customary levels of fat of plant origin that are low in saturated fat content. This hypothesis needs to be tested by comparing a traditional low-fat plant-based diet with a plant-based diet containing customary levels of fat of plant origin in their effectiveness to reverse coronary artery disease.

摘要

全球范围内导致死亡的首要原因是心脏病,而最常见的心脏病类型是冠状动脉疾病。虽然冠状动脉疾病可以通过药物治疗,但它对生活方式干预也有反应。有一种低脂肪的植物性饮食是为逆转冠状动脉疾病而设计的,它在逆转疾病方面非常有效。然而,据我们所知,目前还没有测试过常规脂肪水平的饮食是否也能逆转冠状动脉疾病。尽管如此,越来越多的证据表明,含有常规脂肪水平的饮食可以逆转动脉粥样硬化和冠状动脉疾病。众所周知,植物性脂肪可以降低心血管疾病的风险因素。也有研究表明,摄入常规脂肪水平饮食的素食者患心血管疾病的风险最低。但是最近更具体的数据表明,在富含脂肪的坚果添加到地中海饮食中时,动脉粥样硬化会减少,而对照组中的动脉粥样硬化则会增加。此外,两个临床案例表明,通过添加富含植物脂肪的食物来补充低脂肪的植物性饮食可以逆转冠状动脉疾病。这些数据表明,冠状动脉疾病可能通过含有常规脂肪水平的植物性饮食来逆转。我们假设,通过摄入低饱和脂肪含量的常规脂肪水平的植物性饮食,冠状动脉疾病可能会得到逆转。需要通过比较传统的低脂肪植物性饮食和含有常规脂肪水平的植物性饮食来验证这一假设,以确定它们在逆转冠状动脉疾病方面的有效性。

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