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精神科门诊患者创伤后应激障碍和抑郁障碍共病的预测因素。

Predictors of the co-occurrence of posttraumatic stress disorder and depressive disorder in psychiatric outpatients.

机构信息

Department of Child Studies, Inha University, Incheon, Republic of Korea.

出版信息

Compr Psychiatry. 2019 Feb;89:40-45. doi: 10.1016/j.comppsych.2018.12.005. Epub 2018 Dec 18.

DOI:10.1016/j.comppsych.2018.12.005
PMID:30593972
Abstract

INTRODUCTION

We explored the predictors of co-occurring depressive disorder (DD) in individuals with posttraumatic stress disorder (PTSD) in an outpatient psychiatric setting.

METHODS

Participants (N = 170; mean age = 40.78, SD = 16.15 years; 58.8% women) included 71 adult patients who met the criteria for a PTSD diagnosis and 99 adult patients who met the criteria for a comorbid PTSD/DD diagnosis. Potential predictors included trauma types (focusing on trauma characteristics), history of previous traumatic experiences (i.e., the number of lifetime traumatic events before current trauma and childhood maltreatment), and post-trauma variables (i.e., elapsed time since the current traumatic event and the severity of PTSD symptoms).

RESULTS

A logistic regression analysis-including demographic variables, trauma types, history of previous traumatic experiences, and post-trauma variables that showed significant differences between the two groups-was conducted. The effects of repeated trauma (OR = 13.18, 95% CI [3.44, 50.48], p < .001), the number of lifetime traumatic events (OR = 1.04, 95% CI [1.01, 1.51], p = .044), and childhood maltreatment (OR = 1.23, 95% CI [1.01, 1.51], p = .004) were associated with a greater likelihood of concurrent PTSD/DD.

CONCLUSION

Cumulative characteristics such as maltreatment and the number of lifetime traumatic events before the current trauma as well as repetitive properties of the most recent trauma present a key risk factor for co-occurring PTSD/DD.

摘要

介绍

我们在一个门诊精神病学环境中探讨了创伤后应激障碍(PTSD)患者并发抑郁障碍(DD)的预测因素。

方法

参与者(N=170;平均年龄=40.78,标准差=16.15 岁;58.8%为女性)包括 71 名符合 PTSD 诊断标准的成年患者和 99 名符合 PTSD/DD 共病诊断标准的成年患者。潜在的预测因素包括创伤类型(关注创伤特征)、以前创伤经历的历史(即当前创伤前的终生创伤事件数量和儿童期虐待)和创伤后变量(即当前创伤事件后时间的流逝和 PTSD 症状的严重程度)。

结果

进行了逻辑回归分析,包括两组之间存在显著差异的人口统计学变量、创伤类型、以前创伤经历的历史和创伤后变量。重复创伤(OR=13.18,95%CI [3.44, 50.48],p<.001)、终生创伤事件的数量(OR=1.04,95%CI [1.01, 1.51],p=.044)和儿童期虐待(OR=1.23,95%CI [1.01, 1.51],p=.004)与并发 PTSD/DD 的可能性更大有关。

结论

当前创伤前的虐待和终生创伤事件的数量以及最近创伤的重复特征等累积特征以及重复创伤的特征是并发 PTSD/DD 的关键风险因素。

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