Vazquez Fernando, Fernández-Blázquez Ana, García Beatriz
Servicio de Microbiología, Hospital Universitario Central de Asturias, Oviedo, España; Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, España; Fundación de Investigación Oftalmológica, Instituto Oftalmológico Fernández-Vega, Oviedo, España; Fundación para la Investigación y la Innovación Biosanitaria del Principado de Asturias (FINBA), Oviedo, España; Grupo GEITS de la SEIMC.
Servicio de Microbiología, Hospital Universitario Central de Asturias, Oviedo, España.
Enferm Infecc Microbiol Clin (Engl Ed). 2019 Nov;37(9):592-601. doi: 10.1016/j.eimc.2018.11.009. Epub 2018 Dec 26.
The latest advances in the vaginal microbiome and molecular diagnosis of bacterial vaginosis have allowed for a better knowledge of this entity, characterising aspects of its pathogenesis and the establishment of the vaginal biolayer, the models and new theories of its aetiology, how it is transmitted, with it being considered nowadays as a probable sexually transmitted infection, the separation of other entities such as aerobic vaginosis, its molecular diagnosis and treatment with new molecules to prevent frequent relapses. This entity and the study of the vaginal microbiome have made it possible to consider these infections as a polymicrobial syndrome, putting an end to the dogma: one microorganism, one disease. In addition, a lesser-known entity such as aerobic vaginosis and the methods for its detection are updated.
阴道微生物群和细菌性阴道病分子诊断的最新进展使人们对这一病症有了更深入的了解,明确了其发病机制的各个方面以及阴道生物层的形成、病因学的模型和新理论、传播方式,如今它被认为是一种可能的性传播感染,还明确了与其他病症如需氧菌性阴道炎的区分、其分子诊断以及使用新分子进行治疗以防止频繁复发。这一病症以及对阴道微生物群的研究使人们有可能将这些感染视为一种多微生物综合征,终结了“一种微生物,一种疾病”的教条。此外,还更新了如需氧菌性阴道炎这类鲜为人知的病症及其检测方法。