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硼替佐米诱导的肺毒性:一例病例报告及文献综述

Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature.

作者信息

Kharel Prakash, Uprety Deekchha, Chandra Abhinav B, Hu Yirui, Belur Anuradha Avinash, Dhakal Ajay

机构信息

Department of Hospital Medicine, Geisinger Medical Center, 100 N Academy Ave., Danville, PA 17821, USA.

Renal Division, Brigham and Women's Hospital, Boston, MA, USA.

出版信息

Case Rep Med. 2018 Nov 25;2018:2913124. doi: 10.1155/2018/2913124. eCollection 2018.

Abstract

Bortezomib, a proteasome inhibitor, is an established therapy against multiple myeloma. Bortezomib-induced lung injury, although not appreciated during the introductory time of the medication, has now been highlighted in multiple case reports. The objective of this study is to report a case of bortezomib-induced lung injury, review current literature, and perform exploratory analysis.

摘要

硼替佐米,一种蛋白酶体抑制剂,是一种已被认可的治疗多发性骨髓瘤的药物。硼替佐米引起的肺损伤,尽管在该药物引入初期未被重视,但现在已在多篇病例报告中被强调。本研究的目的是报告一例硼替佐米引起的肺损伤病例,回顾当前文献,并进行探索性分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/6286773/169016172fd6/CRIM2018-2913124.001.jpg

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