Department of Radiology, Yonsei University Health System, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea.
PLoS One. 2018 Dec 31;13(12):e0209754. doi: 10.1371/journal.pone.0209754. eCollection 2018.
The arms-down position increases computed tomography (CT) radiation dose. Iterative reconstruction (IR) could enhance image quality without increasing radiation dose in patients with arms-down position.
To investigate the feasibility of reduced-dose CT with IR for patients with inappropriate arm positioning.
Twenty patients who underwent two-phase abdominopelvic CT including standard-dose and reduced-dose CT (performed with 80% of the radiation dose of the standard protocol) with their arms positioned in the abdominal area were included in this study. Reduced-dose CT images were reconstructed using filtered back projection (FBP), hybrid IR, and iterative model reconstruction (IMR). These images were compared with standard-dose CT images reconstructed with FBP. Objective image noise in the liver and subcutaneous fat was measured by standard deviation for the quantitative analysis. Then, two radiologists qualitatively assessed beam hardening artifacts, artificial texture, noise, sharpness, and overall image quality in consensus.
Reduced-dose CT with all IR levels had lower objective image noise compared to standard-dose CT with FBP reconstruction (P < 0.05). Quantitatively measured beam hardening artifacts were similar in reduced-dose CT with iDose levels 5-6 and fewer with IMR compared to standard-dose CT. In the qualitative analysis, beam hardening artifacts and noise decreased as the IR levels increased. However, artificial texture was significantly aggravated with iDose 5-6 and IMR, and overall image quality significantly worsened with IMR.
IR algorithms can reduce beam hardening artifacts in a reduced-dose CT setting in patients with arms-down position, and an intermediate level of hybrid IR allows radiologists to obtain the best image quality. Because the retrospective and single-center nature of our study limited the number of patients, multicenter prospective clinical studies are required to validate our results.
手臂下放姿势会增加计算机断层扫描(CT)的辐射剂量。迭代重建(IR)可在手臂下放的患者中增强图像质量而不增加辐射剂量。
研究迭代重建在手臂位置不当的患者中进行低剂量 CT 的可行性。
本研究纳入了 20 名进行腹部盆腔双期 CT 检查的患者,包括标准剂量和低剂量 CT(采用标准方案 80%的辐射剂量),这些患者的手臂均放置在腹部区域。使用滤波反投影(FBP)、混合 IR 和迭代模型重建(IMR)对低剂量 CT 图像进行重建。将这些图像与 FBP 重建的标准剂量 CT 图像进行比较。通过标准偏差对肝和皮下脂肪的客观图像噪声进行定量分析。然后,两位放射科医生对束硬化伪影、人工纹理、噪声、锐度和整体图像质量进行一致性的定性评估。
与 FBP 重建的标准剂量 CT 相比,所有 IR 水平的低剂量 CT 具有更低的客观图像噪声(P<0.05)。定量测量的束硬化伪影在 iDose 5-6 水平的低剂量 CT 与 IMR 中相似,而标准剂量 CT 中则较少。在定性分析中,随着 IR 水平的增加,束硬化伪影和噪声减小。然而,IR 5-6 和 IMR 会显著加重人工纹理,而 IMR 会显著降低整体图像质量。
IR 算法可以减少手臂下放患者低剂量 CT 中的束硬化伪影,中等水平的混合 IR 可以让放射科医生获得最佳的图像质量。由于我们的研究是回顾性和单中心的,限制了患者的数量,因此需要进行多中心前瞻性临床研究来验证我们的结果。