Zielinski C
II. Medizinischen Universitätsklinik-Wien.
Wien Med Wochenschr. 1988 Oct 31;138(19-20):517-20.
The acquired immune deficiency syndrome (AIDS) is characterized by a multitude of clinical complications consisting of mainly opportunistic infections and malignancies. Particularly often encountered and life-threatening conditions are therefore due to infections of the respiratory tract (pneumonias caused by pneumocystis carinii or cytomegalovirus) or the central nervous system (e.g. toxoplasmosis or cryptococcosis) and Kaposi sarcoma or highly malignant non-Hodgkin lymphomas. The course of the disease can become even more severe by additional neurologic complications. In patients with AIDS, the use of preparations with proven clinical effectivity for the treatment of opportunistic infections is often hampered by severe side effects.
获得性免疫缺陷综合征（艾滋病）的特征是出现多种临床并发症，主要包括机会性感染和恶性肿瘤。因此，特别常见且危及生命的情况是由呼吸道感染（卡氏肺孢子虫或巨细胞病毒引起的肺炎）或中枢神经系统感染（如弓形虫病或隐球菌病）以及卡波西肉瘤或高度恶性的非霍奇金淋巴瘤所致。疾病进程可能因额外的神经系统并发症而变得更加严重。在艾滋病患者中，用于治疗机会性感染且已证实具有临床有效性的制剂的使用常常受到严重副作用的阻碍。
