Rodrigues Ribeiro Giselle, Heitor Campos Camila, Barbosa Câmara-Souza Mariana, Fraga do Amaral Camilla, Rodrigues Garcia Renata Cunha Matheus
Assistant Professor, School of Dentistry, Salgado de Oliveira University, Niterói, Rio de Janeiro, Brazil.
Assistant Professor, Department of Specific Formation, Nova Friburgo Health Institute, Federal Fluminense University, Nova Friburgo, Rio de Janeiro, Brazil.
Spec Care Dentist. 2019 Mar;39(2):77-83. doi: 10.1111/scd.12351. Epub 2018 Dec 31.
To evaluate masticatory function and oral sensorimotor ability (OSA) in elders with Parkinson's disease (PD) during the levodopa on and off-periods.
Participants were 11 partially and completely edentulous elders with PD. Masticatory function was evaluated by mandibular movements, maximum bite force (MBF), and masticatory performance (MP). Mandibular movements reflecting jaw range of motion (ROM) and jaw movements while chewing silicone test material (Optocal), were evaluated using a kinesiograph. MBF was assessed by strain sensors, and MP was determined using the median Optocal particle size (X ) after 40 masticatory cycles. OSA was evaluated using oral stereognosis test scores and response time. Evaluations were carried out 30 min before levodopa intake (off-period) and within a 3-day interval 1 h after levodopa intake (on-period). Data were analyzed by Student's t-test, considering a significance level of 5%. During the levodopa off-period, elders showed decreased ROM during protrusion and lateral movements, while no difference was found in maximum opening and mandibular movements during chewing. MBF was lower and X was higher during the off-period, indicating worse mastication. However, OSA did not differ between the evaluated times.
Elders with PD had impaired mastication during the levodopa off-period, although OSA was not altered.
评估帕金森病（PD）老年患者在左旋多巴开期和关期的咀嚼功能及口腔感觉运动能力（OSA）。
研究对象为11例部分或完全无牙的PD老年患者。通过下颌运动、最大咬合力（MBF）和咀嚼效能（MP）评估咀嚼功能。使用运动描记仪评估反映下颌运动范围（ROM）的下颌运动以及咀嚼硅酮测试材料（Optocal）时的下颌运动。通过应变传感器评估MBF，并在40个咀嚼周期后使用Optocal颗粒大小中位数（X）确定MP。使用口腔立体觉测试分数和反应时间评估OSA。在左旋多巴摄入前30分钟（关期）和左旋多巴摄入后1小时（开期）的3天间隔内进行评估。采用Student's t检验分析数据，显著性水平为5%。在左旋多巴关期，老年患者在前伸和侧方运动时ROM降低，而在最大开口和咀嚼时的下颌运动方面未发现差异。关期时MBF较低且X较高，表明咀嚼功能较差。然而，评估时间之间OSA没有差异。
PD老年患者在左旋多巴关期咀嚼功能受损，尽管OSA未改变。
