Magee D M, Wing E J
University of Pittsburgh School of Medicine, PA 15213.
Adv Exp Med Biol. 1988;239:245-55. doi: 10.1007/978-1-4757-5421-6_25.
In this series of experiments we have shown that there are at least two mechanisms of CSF production by spleen cells in vitro: nonspecific secretion of CSF by nonimmune cells and immune, antigen-driven production by specific T-lymphocytes. M-CSF was mainly produced in the nonspecific reaction. The immune production by T-lymphocytes consisted of increased CSF production and secretion of multiple species of CSFs.
在这一系列实验中，我们已经表明，体外脾细胞产生脑脊液（CSF）至少有两种机制：非免疫细胞非特异性分泌CSF以及特异性T淋巴细胞的免疫、抗原驱动产生。巨噬细胞集落刺激因子（M-CSF）主要在非特异性反应中产生。T淋巴细胞的免疫产生包括CSF产量增加以及多种CSF的分泌。
