杜兴氏肌营养不良症基因携带者的正常和缺乏肌营养不良蛋白的肌纤维。
Normal and dystrophin-deficient muscle fibers in carriers of the gene for Duchenne muscular dystrophy.
作者信息
Bonilla E, Schmidt B, Samitt C E, Miranda A F, Hays A P, de Oliveira A B, Chang H W, Servidei S, Ricci E, Younger D S
机构信息
Department of Neurology, College of Physicians & Surgeons, Columbia University, Columbia Presbyterian Medical Center, New York, New York.
出版信息
Am J Pathol. 1988 Dec;133(3):440-5.
Dystrophin is the gene product that is affected in Duchenne muscular dystrophy (DMD). Antibodies against dystrophin were used to study the protein in muscle fibers of carriers of the gene. The results showed that DMD carriers have normal and dystrophin-deficient fibers. Dystrophin immunohistochemistry may be helpful for the detection of DMD carriers.
肌营养不良蛋白是在杜兴氏肌营养不良症（DMD）中受影响的基因产物。针对肌营养不良蛋白的抗体被用于研究该基因携带者肌肉纤维中的蛋白质。结果显示，DMD携带者具有正常和缺乏肌营养不良蛋白的纤维。肌营养不良蛋白免疫组织化学可能有助于检测DMD携带者。
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