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妊娠期间的特发性甲状旁腺功能减退症与严重低钙血症

Idiopathic Hypoparathyroidism and Severe Hypocalcemia in Pregnancy.

作者信息

Richa Carine Ghassan, Issa Ali Ihsan, Echtay Akram Salim, El Rawas Mohamad Souheil

机构信息

Department of Endocrinology, Rafic El Hariri University Hospital, Beirut, Lebanon.

Endocrinology Fellow, Lebanese University, Hadath, Lebanon.

出版信息

Case Rep Endocrinol. 2018 Nov 27;2018:8316017. doi: 10.1155/2018/8316017. eCollection 2018.

Abstract

The objective of this study is to report a case of severe hypocalcemia secondary to hypoparathyroidism in a pregnant woman. We report a case of a 45-year-old woman who presented for tonico-clonic seizure in the third trimester of gestation. She was diagnosed with idiopathic hypoparathyroidism for the first time during pregnancy. She was successfully treated with calcium and calcitriol in the rest of her pregnancy with resolution of symptoms but her infant was born with hypercalcemia and secondary hyperparathyroidism due to the late maternal presentation. To the best of our knowledge, hypoparathyroidism is a disorder rarely observed during pregnancy, resulting in most cases from surgical thyroidectomy.

摘要

本研究的目的是报告一例孕妇因甲状旁腺功能减退继发严重低钙血症的病例。我们报告一例45岁女性,在妊娠晚期出现强直阵挛性癫痫发作。她在孕期首次被诊断为特发性甲状旁腺功能减退。在孕期剩余时间里,她通过补充钙剂和骨化三醇成功治疗,症状得以缓解,但由于母亲就诊较晚,她的婴儿出生时患有高钙血症和继发性甲状旁腺功能亢进。据我们所知,甲状旁腺功能减退在孕期很少见,大多数病例是由甲状腺手术切除引起的。

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