Shah Krupa Hitesh, Bhat Shashikala, Shetty Seema, Umakanth Shashikiran
Department of Obstetrics and Gynecology, Melaka Manipal Medical College, Manipal, Karnataka, India.
Department of Medicine, Melaka Manipal Medical College, Manipal, Karnataka, India.
BMJ Case Rep. 2015 Jul 15;2015:bcr2015210228. doi: 10.1136/bcr-2015-210228.
Hypoparathyroidism is an uncommon endocrine deficiency characterised by low serum calcium, absent or inappropriately low parathyroid hormone and normal or high serum phosphorus levels. Parathyroid hormone is essential for calcium homoeostasis. Pregnancy and lactation are known for increased calcium requirement. They cause calcium stress as well as alter its metabolism. Hence, many abnormalities are expected in hypoparathyroidism during pregnancy and lactation. We report a case of pregnancy in postsurgical hypoparathyroidism, which is rarely encountered in antenatal clinics. We describe our clinical, biochemical and therapeutic experience of pregnancy and lactation in this patient with hypoparathyroidism.
甲状旁腺功能减退是一种罕见的内分泌缺乏症,其特征为血清钙水平低、甲状旁腺激素缺乏或水平异常低,以及血清磷水平正常或升高。甲状旁腺激素对钙稳态至关重要。众所周知,妊娠和哺乳期对钙的需求增加。它们会导致钙应激并改变其代谢。因此,妊娠和哺乳期的甲状旁腺功能减退患者可能会出现许多异常情况。我们报告了一例手术后甲状旁腺功能减退患者妊娠的病例,这种情况在产前诊所很少见。我们描述了该甲状旁腺功能减退患者妊娠和哺乳期的临床、生化及治疗经验。