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使用光谱域光学相干断层扫描技术评估单侧非肉芽肿性急性前葡萄膜炎患者视网膜和脉络膜厚度的变化

Evaluation of changes in retinal and choroidal thickness using spectral domain optical coherence tomography in unilateral non granulomatous acute anterior uveitis.

作者信息

Balci O, Tanriverdi C, Aydin A, Ozsutcu M, Gulkilik G, Kocabora M S

机构信息

Clinique universitaire d'ophtalmologie, faculté de médecine, université d'Istanbul Medipol, Istanbul, Turkey.

Clinique universitaire d'ophtalmologie, faculté de médecine, université d'Istanbul Medipol, Istanbul, Turkey.

出版信息

J Fr Ophtalmol. 2019 Feb;42(2):138-145. doi: 10.1016/j.jfo.2018.04.018. Epub 2018 Dec 29.

Abstract

PURPOSE

To assess retinal and choroidal thickness changes in eyes with a first episode of unilateral non granulomatous acute anterior uveitis (AU).

METHODS

Thirty-one patients with acute unilateral non granulomatous AU who had undergone spectral domain optical coherence tomography (SD-OCT) of both eyes were included in this retrospective study. Retinal thickness (RT) as defined by the Early Treatment Diabetic Retinopathy Study (ETDRS) and subfoveal choroidal thickness (SFCT) obtained by SD-OCT were recorded. Healthy fellow eyes of the patients served as the control.

RESULTS

A significant thickening in 1mm of ETDRS subfield and in subfoveal choroid was observed in eyes with acute AU when compared with the unaffected fellow eyes (P=0.005 and P<0.00001, respectively). RT and SFCT of affected eyes did not show a significant difference in terms of HLA-B27 antigen presence or absence (P>0.05, for all).

CONCLUSIONS

Significant posterior segment changes were detected in eyes with acute unilateral non granulomatous AU.

摘要

目的

评估单侧非肉芽肿性急性前葡萄膜炎(AU)首次发作患者眼睛的视网膜和脉络膜厚度变化。

方法

本回顾性研究纳入了31例急性单侧非肉芽肿性AU患者,这些患者均接受了双眼的光谱域光学相干断层扫描(SD - OCT)。记录了由早期糖尿病性视网膜病变研究(ETDRS)定义的视网膜厚度(RT)以及通过SD - OCT获得的黄斑中心凹下脉络膜厚度(SFCT)。患者的健侧眼作为对照。

结果

与未受影响的健侧眼相比,急性AU患者的眼睛在ETDRS 1mm子区域和黄斑中心凹下脉络膜出现了显著增厚(分别为P = 0.005和P < 0.00001)。患眼的RT和SFCT在有无HLA - B27抗原方面未显示出显著差异(所有P>0.05)。

结论

在急性单侧非肉芽肿性AU患者的眼睛中检测到了显著的后段变化。

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