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经视频辅助右小开胸术的二尖瓣修复术的策略特异性耐久性。

Strategy-specific durability of mitral valve repair through the video-assisted right minithoracotomy approach.

机构信息

Cardiovascular Department.

Division of Minimally Invasive Cardiac Surgery.

出版信息

J Cardiovasc Med (Hagerstown). 2019 Mar;20(3):137-144. doi: 10.2459/JCM.0000000000000753.

DOI:10.2459/JCM.0000000000000753
PMID:30601192
Abstract

AIMS

We sought to analyze the early and follow-up results of minimally invasive video-assisted mitral valve repair. With particular focus on degenerative disease, results were stratified according to type of lesion, strategy of repair and surgical technique.

METHODS

We retrospectively built a database over 241 patients who received mitral repair for severe regurgitation through right minithoracotomy in the 2009-17 period. Cause was degenerative in 92.1%, restrictive in 5.8% and mixed in the remainders. Clinical and echocardiographic follow-up (98.7% complete, average duration 2.9 years ± 1.4) was obtained through contact of in-house and territorial cardiologists. Recurrent mitral regurgitation at follow-up was defined as being at least mild-to-moderate (2+).

RESULTS

Operative mortality was 1.7%, and related to the technique in one case. Five-year actuarial survival was 95% ± 2; there was no valve-related death and one reoperation. At follow-up, we observed eight cases of 2+ regurgitation and one instance of 4+ regurgitation (4-year actuarial freedom: 92% ± 4). Freedom from recurrent regurgitation was significantly lower in the 'restrictive' subgroup vs. the 'degenerative' subgroup (P = 0.02); no statistically significant difference in freedom from recurrence was observed among patients who received mitral repair using a 'resect' vs. 'nonresection' strategy (P = 0.46), and in those who received the Totally Endoscopic technique (endoaortic balloon occlusion, no costal spreading) vs. controls (external aortic clamp, costal spreading) (P = 0.98).

CONCLUSION

Durability of minimally invasive mitral repair is optimal. Nonresection repair techniques are at least noninferior to previous approaches based on leaflet resection.

摘要

目的

我们旨在分析微创视频辅助二尖瓣修复的早期和随访结果。特别关注退行性疾病,根据病变类型、修复策略和手术技术对结果进行分层。

方法

我们回顾性地建立了一个数据库,其中包括 2009 年至 2017 年期间通过右小开胸术接受严重反流二尖瓣修复的 241 例患者。病因在 92.1%的患者中为退行性,5.8%为限制性,其余为混合性。通过内部和地区心脏病专家的联系获得了 98.7%完整的临床和超声心动图随访(平均随访时间 2.9 年±1.4 年)。在随访中,我们将至少轻度至中度(2+)的复发性二尖瓣反流定义为反流。

结果

手术死亡率为 1.7%,与技术相关的有一例。5 年生存率为 95%±2;无瓣膜相关死亡和 1 例再次手术。在随访中,我们观察到 8 例 2+反流和 1 例 4+反流(4 年生存率:92%±4)。“限制性”亚组与“退行性”亚组相比,复发性反流的无复发生存率明显较低(P=0.02);接受“切除”与“非切除”修复策略的患者(P=0.46)以及接受全内镜技术(主动脉内球囊阻断,不撑开肋骨)与对照组(体外主动脉夹,撑开肋骨)(P=0.98)的患者之间,无复发性反流的无复发生存率无统计学差异。

结论

微创二尖瓣修复的耐久性是最佳的。非切除修复技术至少不劣于以前基于瓣叶切除的方法。

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