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制定机构阿片类药物处方医师教育计划和阿片类药物处方指南:对处方实践的影响。

Development of an Institutional Opioid Prescriber Education Program and Opioid-Prescribing Guidelines: Impact on Prescribing Practices.

机构信息

Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY.

BioRealm, Culver City, California.

出版信息

J Bone Joint Surg Am. 2019 Jan 2;101(1):5-13. doi: 10.2106/JBJS.17.01645.

Abstract

BACKGROUND

Our institution developed a 1-hour mandatory narcotics-prescribing education program as well as postoperative opioid-prescribing guidelines in response to the opioid epidemic. The purpose of this study was to evaluate the effect of this hospital-wide opioid education and subsequent institution of postoperative opioid guidelines on opioid-prescribing practices after ambulatory surgery.

METHODS

This retrospective study was performed at 1 academic orthopaedic hospital. In November 2016, a 1-hour mandatory opioid education program was completed by all hospital prescribers. Postoperative opioid guidelines were then developed and were disseminated in February 2017. All postoperative narcotic prescriptions after ambulatory procedures performed by 3 separate services (hand, sports, and foot and ankle services) were evaluated over 4 months prior to and after the mandatory opioid education and subsequent release of service-specific guidelines.

RESULTS

Overall, there was a significant decrease in pills and total oral morphine equivalents prescribed after dissemination of guidelines compared with the pre-intervention cohort procedures (p < 0.001) performed by the sports and hand services. With regard to the sports medicine service, the mean difference in pills prescribed was 6.47 pills (95% confidence interval [CI], 5.4 to 7.5 pills) for knee arthroscopy, 5.6 pills (95% CI, 2.5 to 8.7 pills) for shoulder arthroscopy, and 16.3 pills (95% CI, 13.6 to 19.1 pills) for hip arthroscopy. With regard to the hand service, the mean difference in pills prescribed was 13.0 pills (95% CI, 10.2 to 15.8 pills) for level-1 procedures, 12.4 pills (95% CI, 9.9 to 15.0 pills) for carpal tunnel release, and 21.7 pills (95% CI, 18.0 to 25.3 pills) for distal radial fractures. The decrease in pills prescribed in the post-intervention cohort amounts to almost 30,000 fewer opioid pills prescribed per year after these 6 procedures alone. There was no significant change (p > 0.05) in either the number of pills or the oral morphine equivalents prescribed after any of the 3 procedures performed by the foot and ankle service (ankle arthroscopy, bunion surgery, and Achilles tendon repair).

CONCLUSIONS

We developed a prescriber education program and followed up with consensus-based guidelines for postoperative opioid prescriptions. These interventions caused a significant decrease in excessive opioid-prescribing practices after ambulatory orthopaedic surgery at our hospital. We urge initiatives by national orthopaedic organizations to develop and promote education programs and procedure and disease-specific opioid-prescribing guidelines.

摘要

背景

为应对阿片类药物泛滥问题,我们医院开设了 1 小时强制性麻醉药物处方教育课程,并制定了术后阿片类药物处方指南。本研究旨在评估该医院范围内的阿片类药物教育以及随后实施的术后阿片类药物指南对门诊手术后阿片类药物处方的影响。

方法

本研究为单中心回顾性研究。2016 年 11 月,所有医院开处方者均完成 1 小时强制性阿片类药物教育课程。随后制定了术后阿片类药物指南,并于 2017 年 2 月发布。对 3 个独立科室(手、运动医学和足踝科)的 4 个月门诊手术前后,分别评估了 3 个科室的所有术后阿片类药物处方。

结果

与运动医学和手外科科室术前干预组相比,指南发布后,所有科室的口服吗啡等效药物处方量(p < 0.001)均显著减少。具体而言,膝关节镜检查的处方药物平均减少 6.47 片(95%置信区间 [CI],5.4 至 7.5 片),肩关节镜检查的处方药物平均减少 5.6 片(95% CI,2.5 至 8.7 片),髋关节镜检查的处方药物平均减少 16.3 片(95% CI,13.6 至 19.1 片)。对于手外科,1 级手术的处方药物平均减少 13.0 片(95% CI,10.2 至 15.8 片),腕管松解术的处方药物平均减少 12.4 片(95% CI,9.9 至 15.0 片),桡骨远端骨折的处方药物平均减少 21.7 片(95% CI,18.0 至 25.3 片)。这些 6 种手术中,术后干预组的药物处方量平均减少了近 3 万片,这相当于每年减少近 3 万片阿片类药物处方。接受踝关节镜检查、拇囊炎手术和跟腱修复术的足踝外科的处方药物数量或口服吗啡等效物数量均无显著变化(p > 0.05)。

结论

我们制定了处方者教育计划,并随后制定了基于共识的术后阿片类药物处方指南。这些干预措施使我们医院的门诊骨科手术后阿片类药物过度处方的情况显著减少。我们强烈呼吁全国骨科组织制定并推广教育项目和特定于手术及疾病的阿片类药物处方指南。

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