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通过特定手术的处方指南减少阿片类药物的过度处方

Reducing Opioid Overprescribing through Procedure-specific Prescribing Guidelines.

作者信息

Zhang Kevin K, Blum Kevin M, Chu Jacqueline J, Sharma Shuchi, Skoracki Roman J, Moore Amy M, Janis Jeffrey E, Barker Jenny C

机构信息

Department of Plastic and Reconstructive Surgery, The Ohio State University, Columbus, Ohio.

Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio.

出版信息

Plast Reconstr Surg Glob Open. 2023 Jan 20;11(1):e4776. doi: 10.1097/GOX.0000000000004776. eCollection 2023 Jan.

Abstract

UNLABELLED

Despite advances in opioid-sparing pain management, postdischarge opioid overprescribing in plastic surgery remains an issue. Procedure-specific prescribing protocols have been implemented successfully in other surgical specialties but not broadly in plastic surgery. This study examined the efficacy of procedure-specific prescribing guidelines for reducing postdischarge opioid overprescribing.

METHODS

A total of 561 plastic surgery patients were evaluated retrospectively after a prescribing guideline, which recommended postdischarge prescription amounts based on the type of operation, was introduced in July 2020. Prescription and postdischarge opioid consumption amounts before (n = 428) and after (n = 133) guideline implementation were compared. Patient satisfaction and prescription frequency of nonopioid analgesia were also compared.

RESULTS

The average number of opioid pills per prescription decreased by 25% from 19.3 (27.4 OME) to 15.0 (22.7 OME; = 0.001) after guideline implementation, with no corresponding decrease in the average number of postdischarge opioid pills consumed [10.6 (15.1 OME) to 8.2 (12.4 OME); = 0.147]. Neither patient satisfaction with pain management (9.6-9.6; > 0.99) nor communication (9.6-9.5; > 0.99) changed. The rate of opioid-only prescription regimens decreased from 17.9% to 7.6% ( = 0.01), and more patients were prescribed at least two nonopioid analgesics (27.5% to 42.9%; = 0.003). The rate of scheduled acetaminophen prescription, in particular, increased (54.7% to 71.4%; = 0.002).

CONCLUSIONS

A procedure-specific prescribing model is a straight-forward intervention to promote safer opioid-prescribing practices in plastic surgery. Its usage in clinical practice may lead to more appropriate opioid prescribing.

摘要

未标注

尽管在阿片类药物节省型疼痛管理方面取得了进展,但整形外科出院后阿片类药物的过度处方仍然是一个问题。特定手术的处方方案已在其他外科专科成功实施,但在整形外科尚未广泛应用。本研究考察了特定手术处方指南在减少出院后阿片类药物过度处方方面的效果。

方法

在2020年7月引入一项根据手术类型推荐出院后处方量的处方指南后,对561例整形外科患者进行回顾性评估。比较了指南实施前(n = 428)和实施后(n = 133)的处方及出院后阿片类药物消费量。还比较了患者满意度和非阿片类镇痛药物的处方频率。

结果

指南实施后,每张处方的阿片类药丸平均数量从19.3(27.4 OME)降至15.0(22.7 OME;P = 0.001),下降了25%,而出院后阿片类药丸的平均消费数量没有相应减少[从10.6(15.1 OME)降至8.2(12.4 OME);P = 0.147]。患者对疼痛管理的满意度(9.6 - 9.6;P > 0.99)和沟通满意度(9.6 - 9.5;P > 0.99)均未改变。仅使用阿片类药物的处方方案比例从17.9%降至7.6%(P = 0.01),更多患者被处方至少两种非阿片类镇痛药(从27.5%升至42.9%;P = 0.003)。尤其是对乙酰氨基酚的常规处方比例增加(从54.7%升至71.4%;P = 0.002)。

结论

特定手术的处方模式是一种直接的干预措施,可促进整形外科更安全的阿片类药物处方实践。其在临床实践中的应用可能会带来更合适的阿片类药物处方。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5692/9857484/45827ef5dc53/gox-11-e4776-g001.jpg

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