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未成熟和成熟恒牙牙髓坏死的血运重建:一项临床研究。

Revascularization in Immature and Mature Teeth with Necrotic Pulp: A Clinical Study.

作者信息

Neelamurthy Padmaraj S, Kumar Ramachandran A, Balakrishnan Venkatesh, Venkatesan Sokkalingam M, Narayan Gopal S, I Karthikeyan

机构信息

Department of Conservative Dentistry and Endodontics, Indira Gandhi Institute of Dental sciences, Puducherry, India.

Department of Conservative Dentistry and Endodontics, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.

出版信息

J Contemp Dent Pract. 2018 Nov 1;19(11):1393-1399.

Abstract

AIM

The aim of this in vivo study was to evaluate the revascularization procedure both in immature and mature teeth with necrotic pulp and open apices, disinfected with triple antibiotic paste followed by inducing blood clot in the root canal.

MATERIALS AND METHODS

Fifteen patients were selected who presented with immature and mature permanent teeth with pulpal necrosis and open apices. In the first visit, the root canal was accessed with LA and rubber dam isolation; then the canal was disinfected using triple antibiotic paste containing ciprofloxacin, metronidazole, and clindamycin in the ratio of 1:1:1 and closed with IRM. In the second visit, after administering local anesthesia and isolating with a rubber dam, the triple antibiotic paste was washed out by saline irrigation, and apical papilla beyond the confines of the root canal was stimulated with sterile H file to produce a blood clot. Finally, the access was closed using a double seal with mineral trioxide aggregate (MTA) placed apical to cementoenamel junction and resin bonded cement over the MTA. Radiographic examination and pulp sensibility test was done during the follow-up period of 2,4,6,8 and 10 months.

RESULT

After 10 months follow-up, 10 out of 13 patients showed root development and apical closure. The eight patients out of 13 showed root development, apical closure and lateral thickening of radicular dentin and 2 out of 13 patients showed a positive response to electric sensibility test.

CONCLUSION

Within the limitation of this study, it can be concluded that there is evidence of root development, increase in lateral wall thickness, apical closure and positive response to pulp sensibility test in both mature and immature teeth with necrotic pulp.

CLINICAL SIGNIFICANCE

The conventional approach for management of teeth with necrotic pulp and the open apex is altered with the possibility of tissue regeneration within the pulp space and continued root development through revascularization procedures. It also re-establishes the vitality in a previously nonvital and necrosed tooth.

摘要

目的

本体内研究的目的是评估用三联抗生素糊剂消毒并在根管内诱导形成血凝块后,在牙髓坏死且根尖孔开放的未成熟和成熟牙齿中进行的血管再生程序。

材料和方法

选择15例患有牙髓坏死且根尖孔开放的未成熟和成熟恒牙患者。在首次就诊时,用局部麻醉剂打开根管并使用橡皮障隔离;然后使用含有环丙沙星、甲硝唑和克林霉素,比例为1:1:1的三联抗生素糊剂对根管进行消毒,并用IRM封闭。在第二次就诊时,给予局部麻醉并用橡皮障隔离后,用生理盐水冲洗三联抗生素糊剂,并用无菌H锉刺激根管范围以外的根尖乳头以形成血凝块。最后,使用双重封闭,在牙骨质牙釉质界根尖处放置矿物三氧化物凝聚体(MTA),并在MTA上覆盖树脂粘结水门汀封闭入口。在2、4、6、8和10个月的随访期内进行影像学检查和牙髓敏感性测试。

结果

随访10个月后,13例患者中有10例显示牙根发育和根尖闭合。13例患者中有8例显示牙根发育、根尖闭合以及牙根牙本质的侧向增厚,13例患者中有2例对电敏感性测试呈阳性反应。

结论

在本研究的局限性范围内,可以得出结论,在牙髓坏死的成熟和未成熟牙齿中,有证据表明存在牙根发育、侧壁厚度增加、根尖闭合以及对牙髓敏感性测试呈阳性反应。

临床意义

牙髓坏死且根尖孔开放牙齿的传统治疗方法发生了改变,牙髓腔内有组织再生的可能性,并通过血管再生程序使牙根持续发育。它还能使先前无活力和坏死的牙齿重新恢复活力。

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