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采用内收肌肌瓣转移术治疗炎症性肠病患者的复发性阴道直肠瘘、直肠阴道瘘、直肠尿道瘘和袋状阴道瘘。

Gracilis muscle transposition for treatment of recurrent anovaginal, rectovaginal, rectourethral, and pouch-vaginal fistulas in patients with inflammatory bowel disease.

机构信息

Department of Surgery, Caritas Clinic St. Josef, Landshuter Str. 65, 93053, Regensburg, Germany.

出版信息

Tech Coloproctol. 2019 Jan;23(1):43-52. doi: 10.1007/s10151-018-1918-7. Epub 2019 Jan 2.

DOI:10.1007/s10151-018-1918-7
PMID:30604248
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6656797/
Abstract

BACKGROUND

The aim of this study was to evaluate the effectiveness of gracilis muscle transposition (GMT) to treat recurrent anovaginal, rectovaginal, rectourethral, and pouch-vaginal fistulas in patients with inflammatory bowel disease (IBD).

METHODS

A retrospective study was conducted in patients with IBD who had GMT performed by a single surgeon between 2000 and 2018. Follow-up data regarding healing rate, complications, additional procedures, and stoma closure rate was collected.

RESULTS

A total of 30 women and 2 men had GMT. In all patients fistula was associated with Crohn's disease. In 1 female patient, contralateral gracilis transposition was required after a failed attempt at repair. The primary healing rate was 47% (15/32) and the definitive healing rate (healed by the time of data collection and after secondary procedures) was 71% (23/32). Additional surgical procedures due to fistula persistence or recurrence were performed on 17 patients (53%).At least 7 patients (21%) suffered complications including one wound infection with ischemia of the gracilis muscle. Stoma closure was successful in 18 of 31 cases of patients with stoma (58% of the patients).

CONCLUSIONS

GMT for the treatment of recurrent and complex anorectal fistulas in patients with IBD patient is eventually successful in almost 2/3 of patients.

摘要

背景

本研究旨在评估内收肌移位术(GMT)治疗炎症性肠病(IBD)患者复发性阴道直肠瘘、直肠阴道瘘、直肠尿道瘘和袋状阴道瘘的疗效。

方法

对 2000 年至 2018 年间由一位外科医生施行 GMT 的 IBD 患者进行回顾性研究。收集愈合率、并发症、辅助手术和造口关闭率的随访数据。

结果

共 30 名女性和 2 名男性患者接受了 GMT。所有患者的瘘管均与克罗恩病有关。在 1 名女性患者中,初次修复失败后需要对另一侧内收肌进行转位。初次愈合率为 47%(15/32),确定性愈合率(在数据收集时和进行二次手术后愈合)为 71%(23/32)。17 名患者(53%)因瘘管持续或复发而进行了额外的手术。至少有 7 名患者(21%)出现并发症,包括 1 例因内收肌缺血导致的伤口感染。31 例有造口的患者中,有 18 例(患者的 58%)成功关闭造口。

结论

GMT 治疗 IBD 患者复发性和复杂肛门直肠瘘最终在近 2/3 的患者中获得成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/e0697239f17d/10151_2018_1918_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/78db4ea95d1d/10151_2018_1918_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/862ec154a6bc/10151_2018_1918_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/d62ac3758785/10151_2018_1918_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/8b589b1ddc56/10151_2018_1918_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/ae312fc7d24b/10151_2018_1918_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/e0697239f17d/10151_2018_1918_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/78db4ea95d1d/10151_2018_1918_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/862ec154a6bc/10151_2018_1918_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/d62ac3758785/10151_2018_1918_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/8b589b1ddc56/10151_2018_1918_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/ae312fc7d24b/10151_2018_1918_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a8/6656797/e0697239f17d/10151_2018_1918_Fig6_HTML.jpg

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