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妊娠期中性粒细胞性皮肤病:一个不常见的病程。

Neutrophilic Dermatosis in Pregnancy: An Uncommon Course.

作者信息

Villani Alessia, Fabbrocini Gabriella, Napolitano Maddalena, Costa Claudia, Megna Matteo, Ferrillo Maria

机构信息

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

出版信息

Open Access Maced J Med Sci. 2018 Dec 18;6(12):2393-2394. doi: 10.3889/oamjms.2018.453. eCollection 2018 Dec 20.

DOI:10.3889/oamjms.2018.453
PMID:30607199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6311494/
Abstract

Pyoderma gangrenosum (PG) is a neutrophilic-mediated inflammatory skin disease characterised by the rapid onset of painful, hemorrhagic pustules developing into necrotic ulcers occurring predominantly in women aged 20-50 years. According to the literature, all patients reported no change or worsening of the disease during pregnancy. We herein present the case of a 34-year-old woman that developed a neutrophilic dermatosis of the hand reporting complete resolution of the skin disease during pregnancy.

摘要

坏疽性脓皮病(PG)是一种由中性粒细胞介导的炎症性皮肤病,其特征为迅速出现疼痛性出血性脓疱,发展为坏死性溃疡,主要发生于20至50岁的女性。根据文献报道,所有患者在孕期病情均无变化或加重。我们在此报告一例34岁女性手部发生中性粒细胞性皮肤病,该患者在孕期皮肤病完全消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5396/6311494/31a76788b6d2/OAMJMS-6-2393-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5396/6311494/7e4264879f8a/OAMJMS-6-2393-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5396/6311494/31a76788b6d2/OAMJMS-6-2393-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5396/6311494/7e4264879f8a/OAMJMS-6-2393-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5396/6311494/31a76788b6d2/OAMJMS-6-2393-g002.jpg

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本文引用的文献

1
A Case of the Co-Existence of Subcorneal Pustular Dermatosis and Pyoderma Gangrenosum and a Review of the Literature.1例角层下脓疱性皮肤病与坏疽性脓皮病并存病例及文献复习
Open Access Maced J Med Sci. 2018 Jul 8;6(7):1271-1274. doi: 10.3889/oamjms.2018.214. eCollection 2018 Jul 20.
2
Pyoderma gangrenosum during pregnancy - treatment options revisited.妊娠期坏疽性脓皮病-重新探讨治疗选择。
J Eur Acad Dermatol Venereol. 2016 Nov;30(11):1981-1984. doi: 10.1111/jdv.13792. Epub 2016 Jun 29.
3
Pyoderma gangrenosum and pregnancy: an example of abnormal inflammation and challenging treatment.
坏疽性脓皮病与妊娠:异常炎症及挑战性治疗的一个实例
Br J Dermatol. 2016 Jan;174(1):77-87. doi: 10.1111/bjd.14230. Epub 2015 Dec 14.
4
Pyoderma gangrenosum of the hand.手部坏疽性脓皮病
Adv Skin Wound Care. 2014 Feb;27(2):61-4. doi: 10.1097/01.ASW.0000441101.33820.e3.
5
Pyoderma gangrenosum in pregnancy.
Eur J Dermatol. 2009 Sep-Oct;19(5):528-9. doi: 10.1684/ejd.2009.0765. Epub 2009 Jul 29.