Dan M, Somer I, Knobel B, Gutman R
Department of Medicine B, Edith Wolfson Medical Center, Holon, Israel.
Rev Infect Dis. 1988 Nov-Dec;10(6):1204-7. doi: 10.1093/clinids/10.6.1204.
Multiple necrotic soft tissue lesions were observed in the groin of a granulocytopenic patient with Corynebacterium group JK septicemia. Complete healing followed vancomycin therapy. Review of the English-language literature disclosed that skin and soft tissue manifestations were seen in one-quarter of the patients with Corynebacterium group JK septicemia, all of whom were granulocytopenic; in no case of endocarditis were similar findings reported. The majority of lesions consisted of local infections at sites of previous bone marrow biopsy, intravascular catheter insertion, or perianal fissure; they preceded septicemia and were designated primary lesions. Less often, skin and soft tissue manifestations--including papular skin rash, soft tissue abscesses, and necrotic soft tissue lesions--developed in patients with established septicemia and were considered secondary.
在一名患有JK组棒状杆菌败血症的粒细胞减少患者的腹股沟处观察到多处坏死性软组织病变。万古霉素治疗后完全愈合。对英文文献的回顾显示，四分之一的JK组棒状杆菌败血症患者出现皮肤和软组织表现，所有这些患者均为粒细胞减少；在任何心内膜炎病例中均未报告类似发现。大多数病变由先前骨髓活检、血管内导管插入或肛周裂隙部位的局部感染组成；它们先于败血症出现，被称为原发性病变。较少见的情况是，已确诊败血症的患者出现皮肤和软组织表现，包括丘疹性皮疹、软组织脓肿和坏死性软组织病变，这些被认为是继发性的。
