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评估酗酒作为获得性免疫缺陷综合征(艾滋病)的一个风险因素。

Assessing alcoholism as a risk factor for acquired immunodeficiency syndrome (AIDS).

作者信息

Molgaard C A, Nakamura C, Hovell M, Elder J P

机构信息

Division of Epidemiology and Biostatistics, Graduate School of Public Health, San Diego State University, CA 92182.

出版信息

Soc Sci Med. 1988;27(11):1147-52. doi: 10.1016/0277-9536(88)90344-9.

Abstract

Acquired Immunodeficiency Syndrome (AIDS) is characterized by a range of risk factors that determine susceptibility to HIV and the clinical expression of the disease. These include sexual practices, intravenous drug use, and blood exchange. Appropriate preventive measures have been formulated for these risk factors. This paper reviews alcohol abuse as a prominent feature of the homosexual experience, and suggests that it may merit consideration as a risk factor in relation to AIDS. The presumably high prevalence of alcohol abuse among homosexuals and the damaging effects of alcohol on the immune system are discussed as a basis for linking alcoholism, homosexuality, and AIDS. The implications of the potentiating effects of alcohol misuse as the human immunodeficiency virus infiltrates the heterosexual population are presented in terms of high risk populations and the need for additional preventive measures.

摘要

获得性免疫缺陷综合征(艾滋病)的特征是一系列决定对艾滋病毒易感性和疾病临床表现的风险因素。这些因素包括性行为、静脉注射吸毒和血液交换。针对这些风险因素已制定了适当的预防措施。本文回顾了酗酒作为同性恋经历的一个突出特征,并表明它可能值得作为与艾滋病相关的一个风险因素加以考虑。讨论了同性恋者中酗酒的推测高患病率以及酒精对免疫系统的破坏作用,以此作为将酗酒、同性恋和艾滋病联系起来的基础。就高危人群以及采取更多预防措施的必要性而言,阐述了酒精滥用在人类免疫缺陷病毒渗透到异性恋人群中时的增强作用所带来的影响。

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