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肥胖如何影响小儿前交叉韧带重建?

How Does Obesity Impact Pediatric Anterior Cruciate Ligament Reconstruction?

机构信息

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.

出版信息

Arthroscopy. 2019 Jan;35(1):130-135. doi: 10.1016/j.arthro.2018.07.044.

Abstract

PURPOSE

To assess the relationship of elevated body mass index (BMI) on postoperative outcomes, including graft rupture, contralateral anterior cruciate ligament (ACL) tear, new meniscus injuries, isokinetic strength testing, and range of motion (ROM) in a large group of pediatric patients. We also sought to calculate the risk of graft rupture in overweight patients with small femoral or tibial tunnels. The secondary objective was to evaluate the association between BMI and concurrent meniscus tears and the need for meniscectomy at the time of primary ACL reconstruction.

METHODS

We retrospectively reviewed all pediatric patients undergoing primary ACL reconstruction at our institution. BMI percentile for age was used to categorize children as having normal BMI or being overweight or obese per Centers for Disease Control and Prevention guidelines. Demographic data, intraoperative findings and techniques, postoperative complications (including graft rupture, contralateral ACL tear, and meniscus injuries), ROM, and isokinetic strength testing were recorded. Univariate analysis was followed by stepwise, logistic regression to control for confounders.

RESULTS

Of the 1,056 patients included, 535 (50.7%) were male and 521 were (49.3%) female, with a mean age of 15.1 ± 2.4 years. The average BMI was 23.1 ± 4.7. There were 675 (63.9%) children with normal BMI, 228 (21.6%) who were overweight, and 153 (14.5%) who were obese. In multivariate analysis, children with elevated BMI had a higher rate of concurrent meniscus tears compared with those with normal BMI (76.3% vs 70.2%; P = .02) and 1.6 times higher odds of requiring a meniscectomy (95% confidence interval, 1.2-2.2; P < .01). The 723 patients included in the analysis of postoperative complications had a mean follow-up duration of 26.2 ± 3.3 months Postoperatively, BMI did not impact the rate of graft rupture, contralateral ACL injury, or new meniscus tears. There was no increased risk of graft failure in overweight children with smaller graft size (≤8 mm). There was no clinically relevant difference in postoperative ROM or isokinetic strength testing.

CONCLUSIONS

After ACL rupture, overweight and obese children sustained more overall meniscus tears and more irreparable meniscus tears than those with normal BMI. Graft size did not impact the risk of early graft failure in overweight patients. With an appropriate rehabilitation protocol, there was no increased risk of graft rupture, contralateral ACL injury, or new meniscus tear in early follow-up.

LEVEL OF EVIDENCE

Level III, retrospective comparative study.

摘要

目的

评估身体质量指数(BMI)升高与术后结果的关系,包括移植物破裂、对侧前交叉韧带(ACL)撕裂、新半月板损伤、等速力量测试和运动范围(ROM),研究对象为一大组儿科患者。我们还试图计算出在股骨或胫骨隧道较小的超重患者中发生移植物破裂的风险。次要目的是评估 BMI 与同时发生的半月板撕裂以及在初次 ACL 重建时需要半月板切除术之间的关联。

方法

我们回顾性分析了在我院接受初次 ACL 重建的所有儿科患者。根据疾病控制与预防中心的指南,使用 BMI 年龄百分位数将儿童分为正常 BMI、超重或肥胖。记录人口统计学数据、术中发现和技术、术后并发症(包括移植物破裂、对侧 ACL 撕裂和半月板损伤)、ROM 和等速力量测试。进行单变量分析后,采用逐步逻辑回归控制混杂因素。

结果

在纳入的 1056 例患者中,535 例(50.7%)为男性,521 例(49.3%)为女性,平均年龄为 15.1 ± 2.4 岁。平均 BMI 为 23.1 ± 4.7。有 675 例(63.9%)儿童 BMI 正常,228 例(21.6%)超重,153 例(14.5%)肥胖。多变量分析显示,与 BMI 正常的儿童相比,BMI 升高的儿童并发半月板撕裂的发生率更高(76.3%比 70.2%;P=.02),需要半月板切除术的几率高 1.6 倍(95%置信区间,1.2-2.2;P<.01)。在对术后并发症进行分析的 723 例患者中,平均随访时间为 26.2 ± 3.3 个月。术后 BMI 不影响移植物破裂、对侧 ACL 损伤或新半月板撕裂的发生率。对于较小移植物尺寸(≤8mm)的超重儿童,移植物失败的风险没有增加。术后 ROM 或等速力量测试没有明显的临床差异。

结论

在 ACL 断裂后,超重和肥胖儿童的半月板总体撕裂和不可修复的半月板撕裂比 BMI 正常的儿童更多。在超重患者中,移植物尺寸并不影响早期移植物失败的风险。在适当的康复方案下,在早期随访中,没有增加移植物破裂、对侧 ACL 损伤或新半月板撕裂的风险。

证据等级

III 级,回顾性比较研究。

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