Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 13620, Korea.
Department of Brain and Cognitive Science, Seoul National University College of Natural Sciences, Seoul, Korea.
Dysphagia. 2019 Oct;34(5):692-697. doi: 10.1007/s00455-018-09973-6. Epub 2019 Jan 5.
Dysphagia is common in older adults and associated with increased socioeconomic burdens. Recently, sarcopenia is considered to be a possible contributor for dysphagia. The purpose of this study is to investigate the association of dysphagia with sarcopenia in a geriatric population in Korea. This is a cross-sectional study using data from the Korean Longitudinal Study on Health and Aging (KLoSHA). Community-dwelling men and women aged 65 years and older without common causes of dysphagia in Seongnam City, Korea were included (N = 236). Dysphagia was screened using Standardized Swallowing Assessment. Appendicular skeletal muscle mass was calculated by dual-energy X-ray absorptiometry. Grip strength and long-distance corridor walk were assessed. Of 236 subjects, 54 (22.9%) showed dysphagia and 38 (16.1%) showed sarcopenia. Fourteen (5.9%) participants were diagnosed with sarcopenic dysphagia. In multiple logistic regression analysis for dysphagia, sarcopenia was the only significant variable with odds ratio of 2.738 (95% confidence interval 1.160-6.466). Sarcopenia was associated with increased risk of dysphagia in community-dwelling older adults having no common causes of dysphagia even after adjusting for possible confounders. A prospective study with a larger sample size is needed to reveal their causal relationship in the future.
老年人中普遍存在吞咽困难，且与较高的社会经济负担相关。最近，人们认为肌少症可能是导致吞咽困难的一个因素。本研究旨在调查韩国老年人群中吞咽困难与肌少症的相关性。这是一项使用韩国健康老龄化纵向研究（KLoSHA）数据的横断面研究。研究纳入了韩国城南市无常见吞咽困难病因的 65 岁及以上的社区居住的男性和女性（N=236）。使用标准化吞咽评估筛查吞咽困难，通过双能 X 射线吸收法计算四肢骨骼肌质量，评估握力和远距离走廊行走。在 236 名受试者中，54 名（22.9%）存在吞咽困难，38 名（16.1%）存在肌少症。14 名（5.9%）参与者被诊断为肌少性吞咽困难。在吞咽困难的多因素逻辑回归分析中，肌少症是唯一具有显著意义的变量，比值比为 2.738（95%置信区间 1.160-6.466）。即使在调整了可能的混杂因素后，肌少症与社区居住的无常见吞咽困难病因的老年人群中吞咽困难的风险增加相关。未来需要进行具有更大样本量的前瞻性研究以揭示它们的因果关系。
