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New incriminating evidence against IGF2.

作者信息

Ding Wen, Shehadeh Lina A

机构信息

Department of Molecular and Cellular Pharmacology, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA.

Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA.

出版信息

Transl Cancer Res. 2017 Aug;6(Suppl 6):S949-S952. doi: 10.21037/tcr.2017.06.07.

DOI:10.21037/tcr.2017.06.07
PMID:30613484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6320226/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b13/6320226/597cad5c4489/nihms-998317-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b13/6320226/597cad5c4489/nihms-998317-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b13/6320226/597cad5c4489/nihms-998317-f0001.jpg

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New incriminating evidence against IGF2.针对胰岛素样生长因子2(IGF2)的新的有罪证据。
Transl Cancer Res. 2017 Aug;6(Suppl 6):S949-S952. doi: 10.21037/tcr.2017.06.07.
2
Insulin-like growth factor II induces DNA synthesis in fetal ventricular myocytes in vitro.胰岛素样生长因子II在体外诱导胎儿心室肌细胞的DNA合成。
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本文引用的文献

1
Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression.癌细胞分泌的 IGF2 可促使成纤维细胞和骨髓来源的血管祖细胞促进肿瘤进展。
Nat Commun. 2017 Feb 10;8:14399. doi: 10.1038/ncomms14399.
2
miR-30e targets IGF2-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice.微小RNA-30e靶向胰岛素样生长因子2调控的骨髓间充质干细胞、主动脉平滑肌细胞和成脂蛋白E基因敲除小鼠的骨生成。
Cardiovasc Res. 2015 Apr 1;106(1):131-42. doi: 10.1093/cvr/cvv030. Epub 2015 Feb 12.
3
Id1-induced IGF-II and its autocrine/endocrine promotion of esophageal cancer progression and chemoresistance--implications for IGF-II and IGF-IR-targeted therapy.Id1 诱导的 IGF-II 及其自分泌/内分泌促进食管癌的进展和化疗耐药——对 IGF-II 和 IGF-IR 靶向治疗的影响。
Clin Cancer Res. 2014 May 15;20(10):2651-62. doi: 10.1158/1078-0432.CCR-13-2735. Epub 2014 Mar 5.
4
Oesophageal carcinoma.食管癌。
Lancet. 2013 Feb 2;381(9864):400-12. doi: 10.1016/S0140-6736(12)60643-6.
5
A phase II pharmacodynamic study of preoperative figitumumab in patients with localized prostate cancer.一项术前使用菲特鲁单抗治疗局限性前列腺癌的 II 期药效学研究。
Clin Cancer Res. 2012 Jun 15;18(12):3407-13. doi: 10.1158/1078-0432.CCR-12-0482. Epub 2012 May 2.
6
Tumor angiogenesis: molecular pathways and therapeutic targets.肿瘤血管生成:分子途径和治疗靶点。
Nat Med. 2011 Nov 7;17(11):1359-70. doi: 10.1038/nm.2537.
7
Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma.抗胰岛素样生长因子 1 型受体抗体 figitumumab 治疗难治性尤文肉瘤患者的初步疗效。
J Clin Oncol. 2011 Dec 1;29(34):4534-40. doi: 10.1200/JCO.2010.33.0670. Epub 2011 Oct 24.
8
The role of the insulin-like growth factor signaling pathway in non-small cell lung cancer and other solid tumors.胰岛素样生长因子信号通路在非小细胞肺癌和其他实体瘤中的作用。
Cancer Treat Rev. 2012 Jun;38(4):292-302. doi: 10.1016/j.ctrv.2011.07.008. Epub 2011 Sep 9.
9
Hallmarks of cancer: the next generation.癌症的特征:下一代。
Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013.
10
Bone marrow-derived mesenchymal stem cells and the tumor microenvironment.骨髓间充质干细胞与肿瘤微环境。
Cancer Metastasis Rev. 2010 Jun;29(2):249-61. doi: 10.1007/s10555-010-9222-7.