慢性肛门瘙痒患者非特异性肥大肛乳头单纯切除术与期待治疗的随机试验
A randomised trial of simple excision of non-specific hypertrophied anal papillae versus expectant management in patients with chronic pruritus ani.
作者信息
Jensen S L
机构信息
Department of Surgical Gastroenterology C, Rigshospitalet, University of Copenhagen, Denmark.
出版信息
Ann R Coll Surg Engl. 1988 Nov;70(6):348-9.
Forty-one patients with non-specific hypertrophied anal papillae and chronic idiopathic pruritus ani were randomly assigned to simple excision of the anal papillae (n = 21) or expectant management (n = 20). The patients were examined blindly 1 and 4 weeks after treatment and 1 year later. None of the patients were lost to follow-up. Of 21 patients treated with simple excision, 14 (67%) were symptom-free at 1 year after treatment compared to 11 out of 20 patients (55%) maintained on expectant management (P greater than 0.05). It is concluded that simple excision of non-specific hypertrophied anal papillae is without effect on chronic idiopathic pruritus ani.
41例患有非特异性肥大肛乳头和慢性特发性肛门瘙痒症的患者被随机分为两组，一组接受肛乳头单纯切除术（n = 21），另一组接受观察等待处理（n = 20）。在治疗后1周、4周以及1年后对患者进行盲法检查。所有患者均未失访。接受单纯切除术的21例患者中，14例（67%）在治疗后1年无症状，而接受观察等待处理的20例患者中有11例（55%）无症状（P>0.05）。结论是非特异性肥大肛乳头的单纯切除术对慢性特发性肛门瘙痒症无效。
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