• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肛门瘙痒的评估、管理和未来展望:叙述性综述。

Evaluation, management and future perspectives of anal pruritus: a narrative review.

机构信息

Department of Abdominal and General Surgery and Oncology, National Cancer Institute, Santariskiu Str. 1, 08406, Vilnius, Lithuania.

SMK University of Applied Social Sciences, Vilnius, Lithuania.

出版信息

Eur J Med Res. 2023 Feb 2;28(1):57. doi: 10.1186/s40001-023-01018-5.

DOI:10.1186/s40001-023-01018-5
PMID:36732860
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9892672/
Abstract

PURPOSE

The without a time limitation. Most recent search was performed on 1st June 2022.

RESULTS

Thorough history and physical examination are very important in view of multiple possible causes of anal pruritus. Most of the focus during examination is drawn on to the perianal region. A digital rectal examination and an anoscopy are essential. It is necessary aim of this narrative review is to overview the classification, diagnostics, possible treatment options and future perspective of anal pruritus.

METHODS

The search was performed by two authors (AD and MJ) independently in the following electronic databases: PubMed, EMBASE, Web of Science, Cochrane Library, CENTRAL and the Allied and Complementary Medicine Databases (AMED). Search was restricted to English language only to avoid moisture and the use of soaps in the perianal region. Furthermore, the patient should avoid certain foods and increase the intake of fiber. If the symptoms do not resolve, topical steroids, capsaicin (0.006%) and tacrolimus (0.1%) ointments may be used. For intractable cases, intradermal methylene blue injection might give a long-lasting symptom relief.

CONCLUSION

Anal pruritus is a long-term deteriorating quality of life issue. Most of the time it is a symptom with a difficult diagnosis. Thorough history and examination should be performed for the best possible treatment.

摘要

目的

无时间限制。最近的搜索时间为 2022 年 6 月 1 日。

结果

鉴于肛门瘙痒有多种可能的原因,全面的病史和体格检查非常重要。检查时的大部分重点都集中在肛周区域。直肠指检和肛门镜检查是必不可少的。本叙述性综述的目的是概述肛门瘙痒的分类、诊断、可能的治疗选择和未来展望。

方法

两名作者(AD 和 MJ)独立在以下电子数据库中进行了搜索:PubMed、EMBASE、Web of Science、Cochrane 图书馆、CENTRAL 和补充与替代医学数据库(AMED)。仅搜索英文文献,以避免肛周潮湿和使用肥皂。此外,患者应避免某些食物,增加纤维摄入。如果症状没有缓解,可以使用局部类固醇、辣椒素(0.006%)和他克莫司(0.1%)软膏。对于难治性病例,皮内亚甲蓝注射可能会提供持久的症状缓解。

结论

肛门瘙痒是一个长期恶化生活质量的问题。大多数时候,它是一种难以诊断的症状。为了获得最佳治疗效果,应进行全面的病史和检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ade/9893560/e4976da124ba/40001_2023_1018_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ade/9893560/e4976da124ba/40001_2023_1018_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ade/9893560/e4976da124ba/40001_2023_1018_Fig1_HTML.jpg

相似文献

1
Evaluation, management and future perspectives of anal pruritus: a narrative review.肛门瘙痒的评估、管理和未来展望:叙述性综述。
Eur J Med Res. 2023 Feb 2;28(1):57. doi: 10.1186/s40001-023-01018-5.
2
Causes and Management of Pruritus Ani.肛门瘙痒的病因与治疗
Dis Colon Rectum. 2023 Jan 1;66(1):10-13. doi: 10.1097/DCR.0000000000002661. Epub 2022 Oct 27.
3
Pruritus ani: etiology and management.肛门瘙痒症:病因与治疗。
Surg Clin North Am. 2010 Feb;90(1):125-35, Table of Contents. doi: 10.1016/j.suc.2009.09.007.
4
[Pruritus ani].[肛门瘙痒]
Rozhl Chir. 2015 Jul;94(7):269-75.
5
Efficacy and safety of methylene blue injection for intractable idiopathic pruritus ani: a single-arm metaanalysis and systematic review.亚甲蓝注射液治疗顽固性特发性肛门瘙痒症的疗效和安全性:单臂荟萃分析与系统评价
Tech Coloproctol. 2023 Oct;27(10):813-825. doi: 10.1007/s10151-023-02825-y. Epub 2023 Jun 12.
6
Pruritus ani.肛门瘙痒
Aust Fam Physician. 2004 Jul;33(7):511-3.
7
Pruritus ani.肛门瘙痒
Aust Fam Physician. 2010 Jun;39(6):366-70.
8
Anal pruritus: Don't look away.肛门瘙痒:别回避。
World J Gastrointest Endosc. 2024 Mar 16;16(3):112-116. doi: 10.4253/wjge.v16.i3.112.
9
Treatment of intractable pruritus ani.顽固性肛门瘙痒的治疗
Dis Colon Rectum. 1990 Sep;33(9):770-2. doi: 10.1007/BF02052324.
10
Long-term follow-up of intradermal injection of methylene blue for intractable, idiopathic pruritus ani.肛周顽固性特发性瘙痒症皮内注射亚甲蓝的长期随访
Tech Coloproctol. 2019 Feb;23(2):143-149. doi: 10.1007/s10151-019-01934-x. Epub 2019 Feb 7.

引用本文的文献

1
Local excision of perianal skin for pruritus ani: a case report.肛周皮肤局部切除治疗肛门瘙痒症:一例报告
J Surg Case Rep. 2025 Aug 26;2025(8):rjaf664. doi: 10.1093/jscr/rjaf664. eCollection 2025 Aug.
2
From Compression to Itch: Exploring the Link Between Nerve Compression and Neuropathic Pruritus.从压迫到瘙痒:探索神经压迫与神经性瘙痒之间的联系。
Am J Clin Dermatol. 2025 Jan;26(1):23-33. doi: 10.1007/s40257-024-00898-5. Epub 2024 Oct 17.
3
Anal pruritus: Don't look away.肛门瘙痒:别回避。

本文引用的文献

1
Efficacy of dupilumab in chronic prurigo and chronic idiopathic pruritus: a systematic review of current evidence and analysis of response predictors.度普利尤单抗治疗慢性瘙痒症和慢性特发性瘙痒症的疗效:现有证据的系统评价及应答预测因素分析。
J Eur Acad Dermatol Venereol. 2022 Sep;36(9):1541-1551. doi: 10.1111/jdv.18221. Epub 2022 May 31.
2
Modulation of the kappa and mu opioid axis for the treatment of chronic pruritus: A review of basic science and clinical implications.调节κ和μ阿片样物质轴治疗慢性瘙痒:基础科学与临床意义综述
JAAD Int. 2022 Apr 20;7:156-163. doi: 10.1016/j.jdin.2022.03.007. eCollection 2022 Jun.
3
World J Gastrointest Endosc. 2024 Mar 16;16(3):112-116. doi: 10.4253/wjge.v16.i3.112.
JAK inhibitors and COVID-19.
JAK 抑制剂与 COVID-19。
J Immunother Cancer. 2022 Apr;10(4). doi: 10.1136/jitc-2021-002838.
4
The translational revolution of itch.痒觉的转化研究。
Neuron. 2022 Jul 20;110(14):2209-2214. doi: 10.1016/j.neuron.2022.03.031. Epub 2022 Apr 20.
5
Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach.风湿免疫领域的 Janus 激酶靶向治疗:一种基于机制的方法。
Nat Rev Rheumatol. 2022 Mar;18(3):133-145. doi: 10.1038/s41584-021-00726-8. Epub 2022 Jan 5.
6
Characterization of the effects on pruritus by novel treatments for atopic dermatitis.新型特应性皮炎治疗药物对瘙痒影响的特征描述。
J Dtsch Dermatol Ges. 2022 Feb;20(2):150-156. doi: 10.1111/ddg.14678. Epub 2021 Dec 27.
7
Efficacy and safety of oral nalbuphine extended release in prurigo nodularis: results of a phase 2 randomized controlled trial with an open-label extension phase.口服纳布啡缓释片治疗结节性痒疹的疗效和安全性:一项 2 期随机对照试验和开放性扩展阶段的结果。
J Eur Acad Dermatol Venereol. 2022 Mar;36(3):453-461. doi: 10.1111/jdv.17816. Epub 2021 Dec 1.
8
Difelikefalin: First Approval.地氟烷:首次批准。
Drugs. 2021 Nov;81(16):1937-1944. doi: 10.1007/s40265-021-01619-6.
9
Assessment of the anxiety and depression among patients with idiopathic pruritus ani.特发性肛门瘙痒症患者焦虑和抑郁状况的评估
Postepy Dermatol Alergol. 2021 Aug;38(4):689-693. doi: 10.5114/ada.2021.108906. Epub 2021 Sep 17.
10
Chronic itch: emerging treatments following new research concepts.慢性瘙痒:新研究概念指导下的新兴治疗方法。
Br J Pharmacol. 2021 Dec;178(24):4775-4791. doi: 10.1111/bph.15672. Epub 2021 Oct 15.