Nakagawa Masatoshi, Kojima Kazuyuki, Inokuchi Mikito, Kobayashi Kenta, Tanioka Toshiro, Okuno Keisuke, Gokita Kentaro
Department of Gastric Surgery, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
World J Clin Cases. 2018 Dec 26;6(16):1094-1100. doi: 10.12998/wjcc.v6.i16.1094.
To investigate safety and oncological feasibility of laparoscopic total gastrectomy (LTG) in overweight (OW) patients.
Patients who underwent total gastrectomy (110 laparoscopic, 211 open) for gastric cancer between January 1999 and July 2016 were included. Propensity score matching selected 152 patients (76 laparoscopic, 76 open), which were subsequently divided into the OW (≥ 25) or non-OW (< 25) group by body mass index. Postoperative outcomes of laparoscopic versus open approaches were compared between OW and non-OW groups.
In the propensity-matched population, baseline characteristics were comparable between the OW and non-OW groups for the laparoscopy and open groups. In the laparoscopy group, operative time was longer ( = 0.01) in the OW group, however, other perioperative results including complication rates were comparable between the non-OW and OW groups. In the open group, number of retrieved lymph nodes were less ( = 0.03) and local complication rate was more frequent ( = 0.03) in the OW group.
LTG in OW patients remains technically challenging but can be performed safely. Our findings imply that OW has a lesser effect on the laparoscopic versus open approach to total gastrectomy.
探讨腹腔镜全胃切除术(LTG)在超重(OW)患者中的安全性和肿瘤学可行性。
纳入1999年1月至2016年7月期间因胃癌接受全胃切除术的患者(110例腹腔镜手术,211例开放手术)。倾向评分匹配法选取152例患者(76例腹腔镜手术,76例开放手术),随后根据体重指数将其分为超重(≥25)组或非超重(<25)组。比较超重组和非超重组中腹腔镜手术与开放手术的术后结局。
在倾向评分匹配人群中,超重组和非超重组在腹腔镜手术组和开放手术组中的基线特征具有可比性。在腹腔镜手术组中,超重组的手术时间较长(P = 0.01),然而,包括并发症发生率在内的其他围手术期结果在非超重组和超重组之间具有可比性。在开放手术组中,超重组的淋巴结清扫数量较少(P = 0.03),局部并发症发生率较高(P = 0.03)。
超重患者的腹腔镜全胃切除术在技术上仍然具有挑战性,但可以安全进行。我们的研究结果表明,超重对腹腔镜与开放全胃切除术方法的影响较小。