Department of Preventive Medicine, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong Province, China.
Jiang Mei Li Gynecological clinic, Xinzhu, Taiwan.
Skin Res Technol. 2019 Jul;25(4):447-455. doi: 10.1111/srt.12672. Epub 2019 Jan 7.
To investigate the characteristics of hairs in Female pattern hair loss (FPHL) patients and healthy females in Southern China.
Three fundamental hair parameters in different scalp areas of 90 Southern Chinese FPHL patients and 83 healthy controls were analyzed by phototrichogram.
Female pattern hair loss patients showed reduced hair density, hair diameter, and terminal/vellus hair ratio. The reduction correlated with the severity of Ludwig staging. Midscalp was the most affected area in FPHL, but occipital and temporal sites were also involved. In normal women, the highest hair density was observed in midscalp, followed by occipital and temporal areas. Peak hair density at midscalp sites was reached at 20s group, then declined with age. Maximum hair diameter at midscalp and occipital sites occurred in 40s group. Terminal/vellus hair ratio tended to increase with age and peak on 50-60s group.
Reduced hair density and hair diameter, and miniaturization of hair follicles are the characteristics of FPHL in Southern Chinese women. Occipital and temporal sites are also affected in FPHL. Age-associated changes might have an influence on the hair condition. The values of hair parameters obtained in this study will help to establish reference data for better evaluation of hair disorders.
研究中国南方女性型脱发(FPHL)患者和健康女性的毛发特征。
通过毛发图像分析,对 90 例中国南方 FPHL 患者和 83 例健康对照者不同头皮区域的 3 项基本毛发参数进行分析。
FPHL 患者的毛发密度、直径和终末/毳毛比均降低,且与 Ludwig 分期严重程度相关。FPHL 最常累及的头皮区域为中顶区,但枕颞区也受累。在正常女性中,毛发密度最高的头皮区域为中顶区,其次是枕区和颞区。中顶区的毛发密度峰值出现在 20 多岁组,随后随年龄增长而下降。中顶区和枕区的最大毛发直径出现在 40 多岁组。终末/毳毛比随年龄增长而增加,在 50-60 多岁组达到峰值。
毛发密度和直径降低、毛囊小型化是中国南方女性 FPHL 的特征,FPHL 还累及枕颞区。年龄相关的变化可能对头发状况有影响。本研究中获得的毛发参数值将有助于建立参考数据,以便更好地评估毛发疾病。