Abualnadi Noor, Dizon Arthur M, Schiff Lauren
Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina.
Clin Obstet Gynecol. 2019 Mar;62(1):37-47. doi: 10.1097/GRF.0000000000000423.
In this article, we describe a variety of medications that physicians managing outpatient chronic pain should familiarize themselves with to better aid their approach to multimodal pain therapy. Physicians should always consider the use of an adjuvant or coanalgesic drug as first-line treatments. Although many of these medications are not primarily analgesics, in clinical practice they have independent analgesic effects or synergistic analgesic properties when used with opioids. The use of adjunct analgesics reduces opioid-related adverse effects and optimizes pain management. Although there may be some medication overlap with this section and the ERAS section, the purpose of this article is to understand prolonged use in the outpatient setting to reduce opioid use or limit opioid dose with adjuvant therapy.
在本文中，我们描述了多种药物，门诊慢性疼痛管理医生应熟悉这些药物，以便更好地辅助他们进行多模式疼痛治疗。医生应始终考虑将辅助药物或协同镇痛药作为一线治疗方法。尽管这些药物中的许多并非主要的镇痛药，但在临床实践中，它们与阿片类药物合用时具有独立的镇痛作用或协同镇痛特性。使用辅助镇痛药可减少与阿片类药物相关的不良反应，并优化疼痛管理。尽管本节与加速康复外科（ERAS）部分可能存在一些药物重叠，但本文的目的是了解在门诊环境中的长期使用情况，以通过辅助治疗减少阿片类药物的使用或限制阿片类药物剂量。
