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传染病:蚊媒病毒病

Infectious Disease: Mosquito-Borne Viral Illnesses.

作者信息

Allison Jay R, Hogue Amy L, Shafer Charles W, Huntington Mark K

机构信息

University of South Dakota Sanford School of Medicine, 414 E. Clark Street, Vermillion, SD 57069.

University of South Dakota Sanford School of Medicine Department of Family Medicine, 414 E. Clark Street, Vermillion, SD 57069.

出版信息

FP Essent. 2019 Jan;476:11-17.

Abstract

Due to rapid globalization and ease of travel, mosquito-borne viral infections are now a concern for family physicians throughout the United States. Zika virus infection is one such concern. It is spread via mosquito bites or by sexual contact with an infected individual. Most patients are asymptomatic, and when symptoms occur, they are mild and nonspecific. The main concern is the potential of the infection to cause fetal anomalies. Dengue is another mosquito-borne viral infection. Symptoms of initial infection are mild, and may include arthralgias. Subsequent infection with a different serotype can cause life-threatening hemorrhagic fever or shock. Chikungunya virus infection is widespread in the Americas and symptoms are similar to those of dengue. However, it can cause a postviral chronic inflammatory rheumatism in up to half of patients. Yellow fever occurs mostly in sub-Saharan Africa and can cause hepatic failure. Encephalitis viruses, most commonly West Nile in the United States and others such as Japanese encephalitis virus, can cause neuroinvasive disease, most often in older adults. Vaccines are available for yellow fever and Japanese encephalitis viruses but the keys to prevention are insect avoidance, mosquito eradication, and use of mosquito repellants.

摘要

由于全球化的迅速发展和旅行的便捷,蚊媒病毒感染现已成为美国全体家庭医生关注的问题。寨卡病毒感染就是其中之一。它通过蚊虫叮咬或与受感染个体发生性接触传播。大多数患者没有症状,症状出现时也很轻微且不具特异性。主要担忧的是该感染导致胎儿畸形的可能性。登革热是另一种蚊媒病毒感染。初次感染的症状较轻,可能包括关节痛。随后感染不同血清型可导致危及生命的出血热或休克。基孔肯雅病毒感染在美洲广泛传播,症状与登革热相似。然而,多达半数的患者可能会引发病毒后慢性炎症性风湿病。黄热病大多发生在撒哈拉以南非洲地区,可导致肝衰竭。脑炎病毒,在美国最常见的是西尼罗河病毒,还有其他如日本脑炎病毒等,可引起神经侵袭性疾病,最常发生在老年人身上。黄热病和日本脑炎病毒有疫苗可用,但预防的关键是避免接触蚊虫、消灭蚊子以及使用驱蚊剂。

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