Hondo Tatsuya, Eno Shin, Matsuda Keiji, Sairaku Akinori, Kisaka Tomohiko
Department of Cardiology, Chugoku Rosai Hospital, Hiroshima, Japan.
J Cardiol Cases. 2009 Dec 2;1(2):e116-e119. doi: 10.1016/j.jccase.2009.10.006. eCollection 2010 Apr.
A 74-year-old woman was admitted to our hospital with chest pain and shortness of breath. Coronary arteriograms revealed occlusion of a drug-eluting stent, which had been implanted 33 months earlier, in the middle right coronary artery. During percutaneous coronary intervention, distal embolization developed and a thrombus was detected with an aspiration catheter. Serological examinations performed 1 year before and during the present hospitalization revealed positive lupus anticoagulant activity. Thrombophilic tendencies, such as antiphospholipid syndrome, are noteworthy as one of the causative factors in very late stent thrombosis.
一名74岁女性因胸痛和呼吸急促入住我院。冠状动脉造影显示,33个月前植入的一枚药物洗脱支架在右冠状动脉中段闭塞。在经皮冠状动脉介入治疗期间,发生了远端栓塞,并用抽吸导管检测到血栓。本次住院前1年及住院期间进行的血清学检查显示狼疮抗凝物活性呈阳性。作为极晚期支架血栓形成的病因之一,抗磷脂综合征等易栓倾向值得关注。