Chiu Kevin B, Lee Kim M, Robillard Katelyn N, MacLean Andrew G
Tulane National Primate Research Center, Covington, LA, USA.
Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA.
Methods Mol Biol. 2019;1938:265-276. doi: 10.1007/978-1-4939-9068-9_19.
With a rapidly aging population, studies of neuroinflammation and degeneration associated with eugeric aging are becoming critical. Using the unique archive at the Tulane National Primate Research Center as a resource, we have developed tools to quantify morphological changes in astrocytes and microglia across the life span of monkeys. This method can be used for morphometric studies of multiple parameters simultaneously in an unbiased manner.
随着人口迅速老龄化，与正常衰老相关的神经炎症和神经变性研究变得至关重要。利用杜兰国家灵长类动物研究中心独特的档案库作为资源，我们开发了工具来量化猴子整个生命周期中星形胶质细胞和小胶质细胞的形态变化。该方法可用于以无偏倚的方式同时对多个参数进行形态测量研究。
