单克隆抗体CVI-ChNL-68.1可识别鸡体内单核细胞-巨噬细胞谱系的细胞。
The monoclonal antibody CVI-ChNL-68.1 recognizes cells of the monocyte-macrophage lineage in chickens.
作者信息
Jeurissen S H, Janse E M, Koch G, de Boer G F
机构信息
Department of Virology, Central Veterinary Institute, Lelystad, The Netherlands.
出版信息
Dev Comp Immunol. 1988 Fall;12(4):855-64. doi: 10.1016/0145-305x(88)90059-6.
The characteristics of monoclonal antibody CVI-ChNL-68.1, which specifically reacts with a group of chicken non-lymphoid cells, are described. Both tissue distribution shown on cryostat sections using immuno-enzyme histochemistry, and quantitative data obtained on cell suspensions are presented. Functional characteristics of CVI-ChNL-68.1-positive cells, such as antigen uptake and glass adherence, are determined. Results show that CVI-ChNL-68.1 reacts with monocytes, macrophages, and interdigitating cells. Possible relationships between the various non-lymphoid cells are discussed.
描述了单克隆抗体CVI-ChNL-68.1的特性，该抗体可与一组鸡非淋巴细胞发生特异性反应。文中呈现了使用免疫酶组织化学在低温恒温器切片上显示的组织分布，以及在细胞悬液上获得的定量数据。还确定了CVI-ChNL-68.1阳性细胞的功能特性，如抗原摄取和玻璃黏附性。结果表明，CVI-ChNL-68.1可与单核细胞、巨噬细胞和指状突细胞发生反应。文中讨论了各种非淋巴细胞之间可能的关系。
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