头孢孟多所致的低凝血酶原血症
Hypoprothrombinemia due to cefamandole.
作者信息
Conraads V M, Demey H E, Heytens L G, Bossaert L L
机构信息
Department of Intensive Care, University of Antwerp, University Hospital, Belgium.
出版信息
Klin Wochenschr. 1988 Dec 1;66(23):1190-2. doi: 10.1007/BF01727668.
PMID:3062269
Abstract
Two patients are described with severe coagulation disturbances, in one instance leading to extensive skin bleeding, secondary to the use of cefamandole. This cefalosporin antibiotic carries the same N-methylthiotetrazole side chain as moxalactam. Pathogenetic mechanisms leading to hypoprothrombinemia, its prevention and treatment are discussed.
摘要
描述了两名患有严重凝血障碍的患者，其中一例因使用头孢孟多继发广泛皮肤出血。这种头孢菌素抗生素与莫西沙星具有相同的N-甲基硫代四唑侧链。讨论了导致低凝血酶原血症的发病机制、预防和治疗方法。
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