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先天性梗阻性尿路病婴儿的一种潜在严重并发症:继发性假性醛固酮减少症。

A potential serious complication in infants with congenital obstructive uropathy: Secondary pseudohypoaldosteronism.

作者信息

Korkut Sabriye, Akin Leyla, Hatipoglu Nihal, Özdemir Ahmet, Gündüz Zübeyde, Dursun Ismail, Korkmaz Levent, Dursun Ismail, Kurtoglu Selim

机构信息

Department of Neonatology, Erciyes University Medical Faculty, Turkey.

Department of Pediatric Endocrinology, Erciyes University Medical Faculty, Turkey.

出版信息

J Pak Med Assoc. 2019 Jan;69(1):108-112.

Abstract

Patients who have secondary pseudohypoaldosteronism (PHA) in addition to hyponatraemia, hyperpotassaemia and high serum aldosterone levels for the age were included in this retrospective study.Among eight patients, seven patients were diagnosed with PHA secondary to obstructive uropathy (OUP), whereas one patient had PHA secondary to ileostomy. Six patients with OUP had simultaneous urinary tract infection (UTI) and in all except one patient, secondary PHA recovered with only UTI treatment before applying surgical correction. All the patients were younger than 3 months age. In three patients with PUV diagnosis, salt wasting recurred in an UTI episode under 3 months of age.

摘要

本回顾性研究纳入了除低钠血症、高钾血症和该年龄组血清醛固酮水平升高外还患有继发性假性醛固酮减少症(PHA)的患者。在8例患者中,7例被诊断为继发于梗阻性尿路病(OUP)的PHA,而1例患者的PHA继发于回肠造口术。6例OUP患者同时患有尿路感染(UTI),除1例患者外,所有患者在进行手术矫正前仅通过UTI治疗,继发性PHA就得以恢复。所有患者年龄均小于3个月。在3例后尿道瓣膜症诊断患者中,在3个月龄以下的UTI发作期间出现了盐耗竭复发。

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