钕：钇铝石榴石激光和氩激光虹膜切开术。一项前瞻性随机临床试验的长期随访。

Neodymium: YAG and argon laser iridotomy. Long-term follow-up in a prospective, randomized clinical trial.

作者信息

Del Priore L V, Robin A L, Pollack I P

机构信息

Glaucoma Services, Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

Ophthalmology. 1988 Sep;95(9):1207-11. doi: 10.1016/s0161-6420(88)33039-3.

DOI:10.1016/s0161-6420(88)33039-3

PMID:3062535

Abstract

Neodymium:YAG (Nd:YAG) and argon laser iridotomies were compared in a prospective, randomized clinical trial of 43 patients with bilateral chronic pupillary-block glaucoma. All patients had one eye randomly assigned to argon and the fellow eye assigned to Nd:YAG laser treatment. Follow-up ranged from 20 to 42 months. Iridotomy closure was not observed in Nd:YAG-treated eyes, but nine (21%) argon iridotomies required retreatment. Visual loss due to progression of laser-induced lens or corneal damage was not observed in any eye. Nine (21%) argon-treated eyes and eight (19%) Nd:YAG-treated eyes required laser trabeculoplasty for further intraocular pressure (IOP) lowering after iridotomy. Five (12%) argon-treated and two (5%) Nd:YAG-treated eyes required intraocular filtration surgery for long-term IOP control, but this difference was not statistically significant. There were no significant long-term differences between these treatment modalities.

摘要

在一项针对43例双侧慢性瞳孔阻滞性青光眼患者的前瞻性随机临床试验中，对钕:钇铝石榴石（Nd:YAG）激光虹膜切开术和氩激光虹膜切开术进行了比较。所有患者一只眼睛随机分配接受氩激光治疗，另一只眼睛接受Nd:YAG激光治疗。随访时间为20至42个月。Nd:YAG激光治疗的眼睛未观察到虹膜切开术闭合，但9例（21%）氩激光虹膜切开术需要再次治疗。任何一只眼睛均未观察到因激光诱导的晶状体或角膜损伤进展导致的视力丧失。9例（21%）接受氩激光治疗的眼睛和8例（19%）接受Nd:YAG激光治疗的眼睛在虹膜切开术后需要进行激光小梁成形术以进一步降低眼压（IOP）。5例（12%）接受氩激光治疗的眼睛和2例（5%）接受Nd:YAG激光治疗的眼睛需要进行眼内滤过手术以长期控制眼压，但这种差异无统计学意义。这些治疗方式之间没有显著的长期差异。