González-Naranjo Justa Elizabeth, Alfonso-Alfonso Maydelin, Grass-Fernandez Daymet, Morales-Chacón Lilia María, Pedroso-Ibáñez Ivón, Ricardo-de la Fe Yordanka, Padrón-Sánchez Arnoldo
Neurophysiology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, Cuba.
Neurology Department, International Center for Neurological Restoration, 25th Ave, No 15805, 11300 Havana, Cuba.
Behav Sci (Basel). 2019 Jan 8;9(1):6. doi: 10.3390/bs9010006.
Patients diagnosed with Parkinson's disease present sleep disorders with a higher frequency than the general population. The sleep architecture in these patients shows variations with respect to the normal population, so in this work it was decided to investigate the characteristics of the macroarchitecture of sleep in patients diagnosed with Parkinson's disease. A polysomnographic study was carried out on 77 patients diagnosed with Parkinson's disease. All the studies were processed according to the v.2.2, and to the criteria of the 3rd ed. (2014). Processing was carried out using descriptive statistics, as well as non-parametric analysis for comparison between cases and controls. The group of patients showed significant reductions of the N2, N3, and REM sleep stages when compared with a control group, as well as a significant increase in intra-sleep wakefulness. The number of REM⁻NoREM sleep cycles and sleep efficiency showed marked reduction compared to the control group. There was a statistically significant difference in the macroarchitecture of sleep between patients diagnosed with Parkinson's disease and healthy controls.
被诊断患有帕金森病的患者出现睡眠障碍的频率高于普通人群。这些患者的睡眠结构与正常人群相比存在差异，因此在本研究中决定调查被诊断患有帕金森病的患者睡眠宏观结构的特征。对77名被诊断患有帕金森病的患者进行了多导睡眠图研究。所有研究均按照v.2.2以及第3版（2014年）的标准进行处理。使用描述性统计以及非参数分析进行病例与对照之间的比较。与对照组相比，患者组的N2、N3和快速眼动（REM）睡眠阶段显著减少，睡眠中觉醒时间也显著增加。与对照组相比，REM-非快速眼动（NoREM）睡眠周期数和睡眠效率显著降低。被诊断患有帕金森病的患者与健康对照者在睡眠宏观结构上存在统计学显著差异。
