Mondragón-Rezola E, Arratíbel-Echarren I, Ruiz-Martínez J, Martí-Massó J F
Hospital Donostia, San Sebastián, Guipúzcoa, España.
Rev Neurol. 2010 Feb 8;50 Suppl 2:S21-6.
Sleep disorders in Parkinson's disease are present in 60-98% of patients and reduce their quality of life.
To review the pathophysiology, diagnostic approach and management of the different sleep disorders.
We describe the pathophysiology associated with neurodegeneration, due to symptoms (motor and nonmotor) and drug therapies. This article reviews insomnia, excessive daytime sleepiness, circadian sleep disorders and sleep apnea.
Subjective or objective sleepiness assessment should routinely be performed by physicians looking after Parkinson's disease patients. Management is difficult and should be targeted to the specific sleep disorder and its likely cause.
帕金森病患者中60 - 98%存在睡眠障碍，这降低了他们的生活质量。
综述不同睡眠障碍的病理生理学、诊断方法及管理。
我们描述了与神经退行性变相关的病理生理学，包括症状（运动和非运动症状）及药物治疗。本文综述了失眠、日间过度嗜睡、昼夜节律睡眠障碍和睡眠呼吸暂停。
照料帕金森病患者的医生应常规进行主观或客观的嗜睡评估。管理困难，应针对特定的睡眠障碍及其可能的病因。
