Wang Feng, Xu Peng, Cong Fei, Tang Pingping
State Key Laboratory and Institute of Elemento-Organic Chemistry , College of Chemistry , Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) , Nankai University , Tianjin 300071 , China . Email:
Chem Sci. 2018 Sep 24;9(47):8836-8841. doi: 10.1039/c8sc03730b. eCollection 2018 Dec 21.
A general approach to the functionalization of aliphatic C-Si bonds in the presence of silver salts and oxidants has been reported. This strategy encompasses a range of valuable C-Si transformations, including the direct conversions of a C-Si bond to C-OCF, C-OBz, C-OCOCF, C-SCF, C-SCN, and C-N bonds. Among them, trifluoromethoxylation of alkylsilanes is reported for the first time. In addition, mechanistic studies indicate that this reaction may proceed through a radical mechanism.
据报道，在银盐和氧化剂存在下，一种实现脂肪族碳 - 硅键官能化的通用方法。该策略涵盖了一系列有价值的碳 - 硅转化反应，包括将碳 - 硅键直接转化为碳 - 氧三氟甲基键、碳 - 氧苄基键、碳 - 氧羰基三氟甲基键、碳 - 硫三氟甲基键、碳 - 硫氰基键和碳 - 氮键。其中，首次报道了烷基硅烷的三氟甲氧基化反应。此外，机理研究表明该反应可能通过自由基机理进行。
