Savelov A A, Shtark M B, Kozlova L I, Verevkin E G, Petrovskii E D, Pokrovskii M A, Rudych P D, Tsyrkin G M
International Tomography Center, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
Research Institute of Molecular Biology and Biophysics, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.
Bull Exp Biol Med. 2019 Jan;166(3):399-403. doi: 10.1007/s10517-019-04359-6. Epub 2019 Jan 9.
The connections between large neuronal networks were analyzed in 12 patients with ischemic or hemorrhagic strokes and hemiparesis included in the course of the interactive brain stimulation in the area of the primary motor cortex by the analysis of independent components of fMRI. The results obtained in 3 patients are presented. Desynchronization of the visual networks with each other and with the motor networks as well as positive dynamics in Rankin scale and box and blocks test were observed in the patients. These data attest to a decrease in the importance of visual control during movements and probably on partial restoration of prioperception. The important role of interactive brain stimulation and network analysis of fMRI data in neurology are discussed.
通过功能磁共振成像独立成分分析，对12例缺血性或出血性中风伴偏瘫患者在初级运动皮层区域进行交互式脑刺激过程中的大神经元网络连接进行了分析。本文展示了3例患者的研究结果。这些患者出现了视觉网络彼此之间以及与运动网络之间的去同步化，同时Rankin量表、方块搭积木测试呈现出积极变化。这些数据证明运动过程中视觉控制的重要性降低，并且本体感觉可能部分恢复。本文还讨论了交互式脑刺激和功能磁共振成像数据的网络分析在神经病学中的重要作用。
