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自体部分厚度巩膜瓣和供体角膜移植物在青光眼引流装置管侵蚀治疗中的应用。

Autologous Partial-thickness Scleral Flap and Donor Corneal Graft in Management of Tube Erosion of Glaucoma Drainage Device.

机构信息

Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA.

出版信息

J Glaucoma. 2019 Apr;28(4):347-351. doi: 10.1097/IJG.0000000000001186.

Abstract

PURPOSE

To evaluate the outcomes of autologous limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness donor corneal allograft in management of tube erosion of glaucoma drainage device.

METHODS

Consecutive patients who had undergone a limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal graft were reviewed. Primary outcome was surgical success of coverage of the exposed tube without complications or additional surgeries. Secondary outcomes were visual acuity (VA), intraocular pressure, number of glaucoma medications, surgical complications, and additional surgeries.

RESULTS

From March 1, 2016 to August 30, 2017 (18 mo), 8 consecutive cases (7 patients) of tube erosions were included for analysis. Mean follow-up and age were 16.6±5.4 months and 74.4±15.2 years, respectively. Mean number of intraocular surgeries was 4.8±1.6 (range: 3 to 6 surgeries) and intraocular glaucoma surgeries was 2.9±1.7 (range: 1 to 6 surgeries) before tube erosion. There were no intraoperative or postoperative complications or recurrence of tube erosion in any patient. Differences between the preoperative and postoperative number of medications (2.6±1.8, 2.9±1.8, respectively; P=0.171) and intraocular pressure (12.9±6.9, 10.8±3.5 mm Hg, respectively; P=0.209) were not statistically significant. Preoperative and 3-month postoperative VA were identical in all eyes except in 1 eye that the VA improved from 20/300 to 20/70 after repair.

CONCLUSIONS

Combination of limbus-hinged partial-thickness scleral flap and half-moon-shaped split-thickness corneal allograft is a viable surgical option to repair tube erosion.

摘要

目的

评估自体角膜缘铰链式部分厚度巩膜瓣和半月形半厚度供体角膜移植在治疗青光眼引流装置管侵蚀中的疗效。

方法

回顾性分析接受角膜缘铰链式部分厚度巩膜瓣和半月形半厚度角膜移植的连续患者。主要结果是在没有并发症或额外手术的情况下成功覆盖暴露的管。次要结果是视力(VA)、眼压、青光眼药物数量、手术并发症和额外手术。

结果

从 2016 年 3 月 1 日至 2017 年 8 月 30 日(18 个月),共纳入 8 例(7 例患者)管侵蚀患者进行分析。平均随访时间和年龄分别为 16.6±5.4 个月和 74.4±15.2 岁。在管侵蚀之前,平均进行了 4.8±1.6 次眼内手术(范围:3 至 6 次手术)和 2.9±1.7 次眼内青光眼手术(范围:1 至 6 次手术)。所有患者均无术中或术后并发症或管侵蚀复发。术前和术后用药数量(分别为 2.6±1.8、2.9±1.8;P=0.171)和眼压(分别为 12.9±6.9、10.8±3.5mmHg;P=0.209)差异无统计学意义。除 1 只眼修复后视力从 20/300 提高到 20/70 外,所有眼的术前和术后 3 个月的视力均相同。

结论

自体角膜缘铰链式部分厚度巩膜瓣和半月形半厚度供体角膜移植联合应用是修复管侵蚀的可行手术选择。

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