胰岛自体移植全胰切除术患者围手术期管理的回顾性评估：单机构回顾
Retrospective Evaluation of the Perioperative Management of Patients Undergoing Total Pancreatectomy With Islet Autotransplantation: Single Institution Review.
作者信息
McSwain Julie R, Nykamp Madeline, Wolf Bethany J, McMurray Jeffrey D, Skorke Christopher A, Clark Carlee A
机构信息
Creighton University School of Medicine, Omaha, NE.
Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
出版信息
Pancreas. 2019 Feb;48(2):228-232. doi: 10.1097/MPA.0000000000001236.
OBJECTIVE
The aim of this retrospective descriptive study was to examine associations with the perioperative management of patients undergoing total pancreatectomy with islet autotransplantation, which may impact complication rate and hospital length of stay.
METHODS
We retrospectively collected data on 165 patients, and 161 patients were included in the final analysis. Data collected included preoperative, intraoperative, and postoperative patient and procedural characteristics.
RESULTS
Approximately 46.6% of patients experienced 1 or more complications. The occurrence of complications was associated with postoperative day 1 hemoglobin levels, use of intraoperative goal-directed therapy, estimated intraoperative blood loss, and total amount of intraoperative insulin given. Hospital length of stay was significantly associated with number of complications, use of goal-directed therapy, procedure duration, and postoperative day 1 hemoglobin levels.
CONCLUSIONS
Overall, our retrospective descriptive study adds to the emerging body of literature determining optimal perioperative management of patients undergoing total pancreatectomy with islet autotransplantation.
目的
本回顾性描述性研究的目的是探讨与接受胰岛自体移植的全胰切除术患者围手术期管理相关的因素，这些因素可能会影响并发症发生率和住院时间。
方法
我们回顾性收集了165例患者的数据，最终分析纳入了161例患者。收集的数据包括术前、术中和术后患者及手术特征。
结果
约46.6%的患者发生了1种或更多并发症。并发症的发生与术后第1天血红蛋白水平、术中目标导向治疗的使用、估计术中失血量以及术中给予的胰岛素总量有关。住院时间与并发症数量、目标导向治疗的使用、手术持续时间以及术后第1天血红蛋白水平显著相关。
结论
总体而言，我们的回顾性描述性研究为确定接受胰岛自体移植的全胰切除术患者最佳围手术期管理的新兴文献增添了内容。
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