Bahk Young Yil, Cho Pyo Yun, Ahn Seong Kyu, Lee Woo-Joo, Kim Tong-Soo
Department of Biotechnology, College of Biomedical and Health Science, Konkuk University, Chungju 27478, Korea.
Protist Resources Research Division, Nakdonggang National Institute of Biological Resources Sciences, Sangju 37242 Korea.
Korean J Parasitol. 2018 Dec;56(6):625-632. doi: 10.3347/kjp.2018.56.6.625. Epub 2018 Dec 31.
Malaria remains one of the leading health burdens in the developing world, especially in several sub-Saharan Africa countries; and Uganda has some of the highest recorded measures of malaria transmission intensity in the world. It is evident that the prevalence of malaria infection, the incidence of disease, and mortality from severe malaria remain very high in Uganda. Although the recent stable political and economic situation in the last few decades in Uganda supported for a fairly good appreciation of malaria control, the declines in infection, morbidity, and mortality are not sufficient to interrupt transmission and this country is among the top 4 countries with cases of malaria, especially among children under 5 years of age. In fact, Uganda, which is endemic in over 95% of the country, is a representative of challenges facing malaria control in Africa. In this study, we evaluated an active case detection program in 6 randomly selected villages, Uganda. This program covered a potential target population of 5,017 individuals. Our team screened 12,257 samples of malaria by active case detection, every 4 months, from February 2015 to January 2017 in the 6 villages (a total of 6 times). This study assessed the perceptions and practices on malaria control in Kiyuni Parish of Kyankwanzi district, Uganda. Our study presents that the incidence of malaria is sustained high despite efforts to scale-up and improve the use of LLINs and access to ACDs, based on the average incidence confirmed by RDTs.
疟疾仍然是发展中世界主要的健康负担之一，尤其是在撒哈拉以南非洲的几个国家；乌干达是世界上疟疾传播强度记录最高的国家之一。显然，乌干达的疟疾感染率、发病率和严重疟疾死亡率仍然很高。尽管乌干达在过去几十年里政治和经济形势稳定，有利于对疟疾控制有较好的认识，但感染率、发病率和死亡率的下降不足以阻断传播，该国是疟疾病例最多的4个国家之一，尤其是在5岁以下儿童中。事实上，乌干达95%以上的地区为疟疾流行区，是非洲疟疾控制面临挑战的一个代表。在本研究中，我们在乌干达随机选择的6个村庄评估了一个主动病例检测项目。该项目覆盖了5017名潜在目标人群。我们的团队从2015年2月至2017年1月，每4个月在这6个村庄通过主动病例检测筛查12257份疟疾样本（共6次）。本研究评估了乌干达Kyankwanzi区Kiyuni教区对疟疾控制的看法和做法。根据快速诊断检测确认的平均发病率，我们的研究表明，尽管努力扩大和改善长效驱虫蚊帐的使用以及主动病例检测的可及性，但疟疾发病率仍然居高不下。
