Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
Department of Oral Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
World J Surg Oncol. 2019 Jan 10;17(1):13. doi: 10.1186/s12957-019-1559-y.
Metastasis of oral cancer to the buccinator lymph nodes (BN) is uncommon. The antegrade lymphatic flow in patients with normal anatomy and physiology makes metastasis of lower gingival cancer to BN unlikely.
A 67-year-old woman presented with a 46 × 25-mm tumor on her lower gingiva, along with metastatic foci in BN and cervical lymph nodes. After neoadjuvant chemotherapy, she underwent radical resection of the primary tumor and BN, along with neck dissection. Following surgery, she received adjuvant chemoradiotherapy. Two years after treatment, there has been no evidence of tumor recurrence or metastasis.
This is the first report of lower gingival squamous cell carcinoma with metastasis to BN. Metastasis to BN from lower gingival cancer is very rare but should be considered in patients with locally advanced tumors or tumors that metastasize to the submandibular node.
口腔癌转移至颊肌淋巴结（BN）并不常见。在解剖和生理学正常的患者中，向前的淋巴流使得下牙龈癌向 BN 转移的可能性较小。
一名 67 岁女性，下牙龈有一个 46×25mm 的肿瘤，同时 BN 和颈部淋巴结有转移性病灶。新辅助化疗后，她接受了原发肿瘤和 BN 的根治性切除术以及颈淋巴结清扫术。手术后，她接受了辅助放化疗。治疗两年后，未见肿瘤复发或转移的证据。
这是首例报告的下牙龈鳞状细胞癌转移至 BN。BN 来自下牙龈癌的转移非常罕见，但对于局部晚期肿瘤或转移至颌下淋巴结的肿瘤患者，应考虑这种转移。
