Unit Porcine Health Management, Department of Reproduction, Obstetrics & Herd Health, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Boehringer Ingelheim Animal Health GmbH, Ingelheim, Germany.
Vet Rec. 2019 Feb 16;184(7):222. doi: 10.1136/vr.104972. Epub 2019 Jan 10.
This study investigated colonisation and lung lesions at slaughter in pigs from vaccinated (V) and non-vaccinated (NV) sows, in two herds (A and B). In each herd, two sow batches were V against with a commercial bacterin at six and three weeks before farrowing and two sow batches remained NV. From each sow batch, laryngeal swabs were collected from the litters of five primiparous sows at weaning and seven days post-weaning. All samples were tested for by nested PCR. In total, 488 piglets were sampled. At slaughter, the extent of -like pneumonia lesions (lung lesion score (LLS)) was assessed. The colonisation rates with at weaning and seven days post-weaning were (V-A=14.2, NV-A=20.0 (P=0.225); V-B=0.9, NV-B=0.8 (P=0.948)) and (V-A=0.8, NV-A=7.0 (P=0.039); V-B=1.8, NV-B=2.5 (P=0.738)), respectively. The average LLS (in per cent) was V-A=15.5, NV-A=26.4 (P=0.021); V-B=9.7, NV-B=8.4 (P=0.541). In conclusion, in herd A, with a substantially higher level of piglet colonisation at weaning than herd B, offspring from V sows had a significantly lower colonisation rate seven days post-weaning and a significantly lower LLS at slaughter compared with the offspring of the NV sows. This implies that sow vaccination might be useful for control of infections, although significant results may not be achieved at all times (such as in herd B).
本研究调查了接种（V）和未接种（NV）母猪的猪在屠宰时的定植和肺部病变，涉及两个猪群（A 和 B）。在每个猪群中，两批母猪在分娩前六周和三周用商业菌苗进行 V 接种，两批母猪保持 NV 状态。从每批母猪中，在断奶时和断奶后七天从五头初产母猪的仔猪中采集喉拭子。所有样本均通过巢式 PCR 检测 。共采样 488 头仔猪。在屠宰时，评估了类肺炎病变（肺病变评分（LLS））的严重程度。断奶和断奶后七天的定植率分别为（V-A=14.2，NV-A=20.0（P=0.225）；V-B=0.9，NV-B=0.8（P=0.948））和（V-A=0.8，NV-A=7.0（P=0.039）；V-B=1.8，NV-B=2.5（P=0.738））。平均 LLS（百分比）分别为 V-A=15.5，NV-A=26.4（P=0.021）；V-B=9.7，NV-B=8.4（P=0.541）。总之，在猪群 A 中，仔猪的定植率在断奶时明显高于猪群 B，与 NV 母猪的仔猪相比，V 母猪的仔猪在断奶后七天的定植率明显较低，屠宰时的 LLS 也明显较低。这意味着母猪接种可能有助于控制 感染，尽管并非在所有时候都能取得显著效果（例如在猪群 B 中）。
