Clinical Immunology Research Center, Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Nursing Department, Zabol University of Medical Sciences, Zabol, Iran.
Breast Cancer Res Treat. 2019 Apr;174(3):585-596. doi: 10.1007/s10549-019-05131-0. Epub 2019 Jan 10.
Breast cancer is the most common type of cancer in women around the world, and this applies to the Middle East as well. The goal of all medical care and treatment is to improve the quality of life (QoL) of patients. Accordingly, the present study aimed at evaluating the QoL of patients with breast cancer in the Middle East region.
In this meta-analysis, three electronic databases (PubMed, Web of Science, and Scopus) were searched from inception until August 2018. The hoy et tool was used to evaluate the quality of the articles included in the meta-analysis. The search, screening, quality evaluation, and data extraction were carried out by two of the researchers.
Thirty-six studies conducted on 8347 Middle Eastern women with breast cancer entered the final stage. QoL was assessed by the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire in 20 studies, with 6034 patients. The mean of the reported QoL was between 31.1 and 75.6. Based on the results of the random effect method, the overall mean of the QoL was 60.5 (95% confidence interval 56.0, 65.0; I2 = 99.0%). In six studies performed on 1053 individuals, QoL was classified as good, moderate, or poor. Less than one-third of patients (21%) had a good QoL.
Since less than one-third of patients had a good QoL, it seems necessary to design and implement an integrated and multidimensional educational program to improve QoL of patients with breast cancer.
乳腺癌是全世界女性最常见的癌症类型，这也适用于中东地区。所有医疗保健和治疗的目标都是提高患者的生活质量（QoL）。因此，本研究旨在评估中东地区乳腺癌患者的生活质量。
在这项荟萃分析中，从创建到 2018 年 8 月，我们在三个电子数据库（PubMed、Web of Science 和 Scopus）中进行了搜索。使用 hoy et 工具评估荟萃分析中包含的文章的质量。搜索、筛选、质量评估和数据提取由两名研究人员进行。
36 项针对 8347 名中东乳腺癌女性的研究进入了最后阶段。20 项研究使用欧洲癌症研究和治疗组织生活质量问卷评估了生活质量，涉及 6034 名患者。报告的生活质量平均值在 31.1 到 75.6 之间。根据随机效应方法的结果，生活质量的总体平均值为 60.5（95%置信区间 56.0，65.0；I2=99.0%）。在 6 项针对 1053 人的研究中，生活质量被分为良好、中等或较差。不到三分之一的患者（21%）生活质量良好。
由于不到三分之一的患者生活质量良好，因此似乎有必要设计和实施一个综合的、多维度的教育计划，以提高乳腺癌患者的生活质量。
