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通过旋转血栓弹力图检测体外膜肺氧合诱导的纤维蛋白溶解并通过氧合器更换进行治疗。

Extracorporeal membrane oxygenation-induced fibrinolysis detected by rotational thromboelastometry and treated by oxygenator exchange.

作者信息

Durila Miroslav, Smetak Tomas, Hedvicak Pavel, Berousek Jan

机构信息

1 Department of Anaesthesiology and Intensive Care Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.

2 Department of Cardiovascular Surgery, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.

出版信息

Perfusion. 2019 May;34(4):330-333. doi: 10.1177/0267659118824218. Epub 2019 Jan 11.

Abstract

Coagulopathy and bleeding is a frequent phenomenon in patients on extracorporeal membrane oxygenation. The cause may be multifactorial and it may change over time. We present a case when bleeding was caused by hyperfibrinolysis induced by oxygenator. The diagnosis was established by comparing thromboelastometry result from blood obtained before and after oxygenator. Hyperfibrinolysis and bleeding could be successfully treated merely by oxygenator exchange.

摘要

凝血功能障碍和出血是体外膜肺氧合患者中的常见现象。其原因可能是多因素的,且可能随时间变化。我们报告一例由氧合器诱导的高纤维蛋白溶解导致出血的病例。通过比较氧合器前后采集血液的血栓弹力图结果来确诊。仅通过更换氧合器就能成功治疗高纤维蛋白溶解和出血。

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