School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, 221116, China.
Chem Commun (Camb). 2019 Jan 24;55(9):1283-1286. doi: 10.1039/c8cc08962k.
Under cooperative catalysis of iridium and a Brønsted acid, different C4-substituted azlactones react with vinyl benzoxazinones via a formal [4+2] cycloaddition or substitution reaction in a chemo- and stereoselective mode. Furthermore, the catalytic asymmetric version of the formal [4+2] cycloaddition established cooperative catalysis of iridium and a chiral thiourea-tertiary amine.
在铱和布朗斯台德酸的协同催化下，不同的 C4-取代氮丙啶酮通过形式上的[4+2]环加成或取代反应，以化学和立体选择性的方式与乙烯基苯并恶嗪酮反应。此外，形式上的[4+2]环加成的催化不对称版本建立了铱和手性硫脲-叔胺的协同催化。
