Key Lab for Colloid and Interface Chemistry of Education Ministry , Shandong University , No. 27 Shanda South Road , Jinan 250100 , China.
State Key Laboratory of Organometallic Chemistry , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , Shanghai 200032 , China.
Org Lett. 2019 Feb 1;21(3):692-695. doi: 10.1021/acs.orglett.8b03880. Epub 2019 Jan 11.
With the synergistic activation of alkynyl alcohols and alkynyl enones by a single gold catalyst, diverse multisubstituted spirocyclopenta[ c]furans were synthesized in good to excellent yields under mild conditions. Three rings were constructed efficiently in one pot from easily available acyclic starting materials.
通过单一金催化剂协同激活炔醇和炔基烯酮，在温和条件下以良好至优异的收率合成了多种多取代螺环[ c]呋喃。三键在一锅反应中从易得的无环起始原料高效构建。
