a Department of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine (LSHTM) , London , UK.
b Swiss Centre for International Health, Swiss Tropical and Public Health Institute , Basel , Switzerland.
Hum Vaccin Immunother. 2019;15(7-8):1615-1627. doi: 10.1080/21645515.2018.1564436. Epub 2019 Feb 20.
Europe is increasingly described as the region in the world with the least confidence in vaccination, and particularly in the safety of vaccines. The aim of this systematic literature review was to gather and summarise all peer-reviewed and grey literature published about determinants of Human Papillomavirus (HPV) vaccine hesitancy in Europe. Ten thematic categories were identified across the 103 articles which were included in the review. Participants from European studies most commonly reported issues with the quantity and quality of information available about HPV vaccination; followed by concerns about potential side effects of the vaccine; and mistrust of health authorities, healthcare workers, and new vaccines. Comparative analyses indicated that confidence determinants differed by country and population groups. This evidence supports the need to develop context-specific interventions to improve confidence in HPV vaccination and design community engagement strategies aiming to build public trust.
欧洲正逐渐被描述为世界上对疫苗接种信心最低的地区，尤其是对疫苗安全性的信心。本系统文献综述的目的是收集和总结所有已发表的关于 HPV 疫苗犹豫的同行评议和灰色文献，并在综述中进行了总结。在纳入的 103 篇文章中，共确定了 10 个主题类别。来自欧洲研究的参与者最常报告的问题是关于 HPV 疫苗接种的信息数量和质量；其次是对疫苗潜在副作用的担忧；以及对卫生当局、医疗保健工作者和新疫苗的不信任。比较分析表明，信心决定因素因国家和人群群体而异。这一证据支持需要制定具体国情的干预措施，以提高 HPV 疫苗接种的信心，并设计旨在建立公众信任的社区参与策略。
